Results 91 to 100 of about 218,816 (278)

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

open access: yesAdvanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat   +11 more
wiley   +1 more source

Stochastic-hydrodynamic model of halo formation in charged particle beams

open access: yesPhysical Review Special Topics. Accelerators and Beams, 2003
The formation of the beam halo in charged particle accelerators is studied in the framework of a stochastic-hydrodynamic model for the collective motion of the particle beam.
Nicola Cufaro Petroni   +3 more
doaj   +1 more source

Evaluation of paleo-wave conditions from oscillatory structures preserved in cretaceous sediments of Baja California

open access: yesCiencias Marinas, 1993
Measurements were obtained of spacing (E), dip and height of oscillatory ripples (hum- mochyylswaley cross-stratification) preserved within the sections of Punta Banda and Peñasco La Lobera in the Late Cretaceous Rosario Formation, in Baja California ...
LA Cupul-Magaña, J Ledesma-Vázquez
doaj   +1 more source

Exploring the membrane theory of entanglement dynamics

open access: yesJournal of High Energy Physics, 2020
Recently an effective membrane theory valid in a “hydrodynamic limit” was proposed to describe entanglement dynamics of chaotic systems based on results in random quantum circuits and holographic gauge theories. In this paper, we show that this theory is
Márk Mezei, Julio Virrueta
doaj   +1 more source

From Clinic to Computation: Multiscale Bioengineering Strategies for Durable Biological Aortic Valve Replacements

open access: yesAdvanced Functional Materials, EarlyView.
Bioprosthetic aortic valves have revolutionized the treatment of aortic stenosis, but their durability is limited by structural valve deterioration (SVD). This review focuses on the pericardial tissue at the heart of these valves, examining how its mechanical properties and calcification drive fatigue and failure.
Gabriele Greco   +7 more
wiley   +1 more source

Hydrodynamic limit for interacting Ornstein–Uhlenbeck particles

open access: yesStochastic Processes and their Applications, 2002
Let us consider a system of \(N\) interacting Ornstein-Uhlenbeck particles, described by a stochastic differential equation \[ dq_ {i} = v_ {i}\,dt, \quad dv_ {i} = -2\sum _ {i\neq j} \nabla V(q_ {i}- q_ {j})\,dt - \frac {\gamma }2 v_ {i}\,dt + \sqrt {\frac {\gamma }{\beta }}\,dW_ {i}, \quad 1\leq i\leq N, \] in \((\mathbb T^ {d}\times \mathbb R^ {d})^
openaire   +2 more sources

Complexation‐Mediated Diffusion‐Limited Crystal Growth: A General Framework for Anisotropic Crystal Growth in Cu‐Based Perovskites

open access: yesAdvanced Functional Materials, EarlyView.
A Complexation‐Mediated Diffusion‐Limited Growth (CMDLG) framework is established to rationalize the anisotropic growth of lead‐free perovskites. Integrating coordination chemistry with mass transport kinetics, this study theoretically derives and experimentally validates that stable iodocuprate complexes induce a diffusion‐limited regime.
Hyunmin Lee   +5 more
wiley   +1 more source

LONGITUDINAL DYNAMICS IN A LENNARD-JONES BINARY LIQUID: CROSSOVER FROM HYDRODYNAMICS TO THE MOLECULAR REGIME

open access: yesCondensed Matter Physics, 2004
Longitudinal collective dynamics of an equimolar Lennard-Jones KrAr mixture is studied in detail in a wide range of spatial and time scales. Combining both the molecular dynamics simulations and analytical generalized collective mode approach, we ...
T.Bryk, I.Mryglod
doaj   +1 more source

Shaping of Biohybrid Functional Living Materials

open access: yesAdvanced Functional Materials, EarlyView.
This work demonstrates a strategy for shaping living mycelium into functional materials by directing its natural growth. Nanoparticles armor hyphae, micron‐scale particles entangle within the network, and printed hydrogel architectures steer expansion, creating defined geometries.
Sarah Schyck   +3 more
wiley   +1 more source

Light Activated Induction of Cuproptosis in Resistant Cancer Cells Using Polymeric BODIPY Nanoparticles for Photoactivated Chemotherapy

open access: yesAdvanced Functional Materials, EarlyView.
This article presents a photo‐responsive nanoparticle platform that precisely triggers copper‐dependent cuproptotic cell death in (drug‐resistant) cancer cells. The system remains stable and inactive in the dark but releases cytotoxic species upon red‐light irradiation, achieving potent activity in drug‐resistant breast cancer cells.
Ricarda Zimmermann   +2 more
wiley   +1 more source

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