Results 41 to 50 of about 59,912 (247)

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Exploring Motion Stability of a Novel Semi-Submersible Platform for Offshore Wind Turbines

Energies
The stability of offshore floating wind turbine foundation platforms is a fundamental requirement for the efficiency and safety of wind power generation systems.
Hongxu Zhao, Xiang Wu, Zhou Zhou
doaj   +1 more source

Unleashing the Power of Machine Learning in Nanomedicine Formulation Development

Advanced Functional Materials, EarlyView.
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore, Cristiano Pesce, Antonietta Greco, Claudia Pisante, Greta Avancini, Valentina Di Francesco, Yosi Shamay, Paolo Decuzzi   +7 more
wiley   +1 more source

Coupled response analysis of dual lifting vessels during collaborative lifting topside module

Brodogradnja
Offshore assembly and disassembly operations represent a multi-billion-dollar market potential. Collaborative lifting by multiple vessels has emerged as a new operating paradigm for integrated offshore facilities assembly and disassembly.
Dejiang Li, Qiutong Tan, Jiwei Liu, Long Zheng, Chao Hu   +4 more
doaj   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

A Pull‐Out Mooring Wave Energy Converter: Design, Analysis, and Application

Advanced Science
Wave energy converters (WEC), as alternative power sources for marine equipment, play a crucial role in promoting the development and utilization of ocean resources.
Weihan Xu, Junru Chen, Shanghao Gu, Xingya Feng, Fei Wang   +4 more
doaj   +1 more source

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

Advanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon, Hee Su Sohn, Jong Sang Yoon, So Won Jeon, Hee Gyeong Ko, Min‐Ho Kang, Jisun Lee, Jae‐Hwan Nam, Louis T. Merriam, Edy Y. Kim, Han Young Kim   +10 more
wiley   +1 more source

Persistent Hydrodynamic Cues Elicit Orientation-Specific Behavioral Sensitivities and Kinematic Responses in Dispersed Crab Larvae

Frontiers in Marine Science, 2020
The estuarine mud crab Panopeus herbstii navigates a complex, but structured, hydrodynamic environment throughout its life history. The effects of hydrodynamic cues associated with turbulent flows on larval behavior are relatively well understood in the ...
Aaron C. True, Donald R. Webster, Marc J. Weissburg, Jeannette Yen   +3 more
doaj   +1 more source

A Numerical Study on Hydrodynamic Energy Conversions of OWC-WEC with the Linear Decomposition Method under Irregular Waves

Energies, 2021
A numerical study was performed to investigate the applicability of the linear decomposition method for the hydrodynamic energy conversion of an oscillating-water-column type wave energy converter (OWC-WEC).
Jeong-Seok Kim, Kyong-Hwan Kim, Jiyong Park, Sewan Park, Seung Ho Shin   +4 more
doaj   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source