Results 51 to 60 of about 9,109 (267)

Generating Cell Surface Nucleated Hydrogels with an Artificial Membrane‐Binding Transglutaminase

Advanced Functional Materials, EarlyView.
Cell‐based therapies require advanced strategies to enhance cell delivery and bioactivity. Cell membrane engineering offers an avenue to impart new functions to delivered cells to boost their viability and function. Here, an artificial membrane‐binding transglutaminase is generated and biophysically characterized.
Rosalia Cuahtecontzi Delint, Tao Li, Kapil D. Patel, Will H. Zhang, Ben M. Carter, Graham J. Day, Adam W. Perriman   +6 more
wiley   +1 more source

Relativistic Binary Precession: Impact on Eccentric Massive Binary Black Hole Accretion and Hydrodynamics

The Astrophysical Journal
Recent hydrodynamical simulations have shown that circumbinary gas disks drive the orbits of massive binary black holes (BHs) to become eccentric, even when general relativistic (GR) corrections to the orbit are significant. Here, we study the GR apsidal
Stanislav DeLaurentiis, Zoltán Haiman, John Ryan Westernacher-Schneider, Luke Major Krauth, Jordy Davelaar, Jonathan Zrake, Andrew MacFadyen   +6 more
doaj   +1 more source

Integrative Approaches for DNA Sequence‐Controlled Functional Materials

Advanced Functional Materials, EarlyView.
DNA is emerging as a programmable building block for functional materials with applications in biomimicry, biochemical, and mechanical information processing. The integration of simulations, experiments, and machine learning is explored as a means to bridge DNA sequences with macroscopic material properties, highlighting current advances and providing ...
Aaron Gadzekpo, Ewa Anna Oprzeska‐Zingrebe, Mariana Kozlowska, Lennart Hilbert, Iliya D. Stoev   +4 more
wiley   +1 more source

3D Radiation-hydrodynamical Simulations of Shadows on Transition Disks

The Astrophysical Journal Letters
Shadows are often observed in transition disks, which can result from obscuring by materials closer to the star, such as a misaligned inner disk. While shadows leave apparent darkened emission as observational signatures, they have significant dynamical ...
Shangjia Zhang, Zhaohuan Zhu
doaj   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

Advanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang, Shuang Feng, Jie Luo, Kaige Xu, Junfeng Guo, Xingyue Zhang, Mengxue Yuan, Qiang Luo, Yu Huang, Chaoqiang Fan, Kibret Mequanint, Donghui Zhu, Malcolm Xing, Shiming Yang   +13 more
wiley   +1 more source

Galaxy catalogs from the Sage Semi-Analytic Model calibrated on The Three Hundred hydrodynamical simulations: A method to push the limits toward lower mass galaxies in dark matter only clusters simulations [PDF]

EPJ Web of Conferences
The new generation of upcoming deep photometric and spectroscopic surveys will allow us to measure the astrophysical properties of faint galaxies in massive clusters. This would demand to produce simulations of galaxy clusters with better mass resolution
Gómez Jonathan S., Yepes G., Muñoz A. Jiménez, Cui W.   +3 more
doaj   +1 more source

FLAMINGO: calibrating large cosmological hydrodynamical simulations with machine learning. [PDF]

Mon Not R Astron Soc, 2023
Kugel R, Schaye J, Schaller M, Helly JC, Braspenning J, Elbers W, Frenk CS, McCarthy IG, Kwan J, Salcido J, van Daalen MP, Vandenbroucke B, Bahé YM, Borrow J, Chaikin E, Huško F, Jenkins A, Lacey CG, Nobels FSJ, Vernon I.   +19 more
europepmc   +1 more source

Quantum‐Grade Nanodiamonds from a Single‐Step, Industrial‐Scale Pressure and Temperature Process

Advanced Functional Materials, EarlyView.
Novel method for creation of nitrogen‐vacancy centers in 50‐nm nanodiamonds based on high‐temperature plastic deformation is demonstrated. Compared to the electron irradiation approach, it yields nitrogen‐vacancy centers with significantly improved charge stability, T1 relaxation time, and optical Rabi contrast.
Yahua Bao, Michal Gulka, Parkarsh Kumar, Jakub Copak, Priyadharshini Balasubramanian, Yuliya Mindarava, Rémi Blinder, Michael Olney‐Fraser, Haotian Wen, Hana Spanielova, Helen Zhi Jie Zeng, Benjamin Whitefield, Igor Aharonovich, Jaroslav Hruby, Fedor Jelezko, J. Daniel Belnap, Shery L. Y. Chang, Petr Cigler   +17 more
wiley   +1 more source

Shape‐Morphing Nanoengineered Hydrogel Ribbons as Hemostats

Advanced Functional Materials, EarlyView.
This study introduces a self‐assembling, shape‐morphing nanoengineered hydrogel ribbon system that rapidly forms porous aggregates in situ for efficient hemostasis in trauma and surgical applications. Abstract Rapid and effective hemorrhage control remains a major challenge in trauma and surgical care, particularly for complex or noncompressible wounds.
Ryan Davis Jr, Saptarshi Biswas, Jacob Aragon, Asaf Dana, Jasmine Sureka, Vaaridhi Ramanuja, Jeevika Thazhaiselvam, Sarah E. Miller, Taylor H. Ware, Akhilesh K. Gaharwar   +9 more
wiley   +1 more source