Results 51 to 60 of about 291,132 (268)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Novel anomalies for like-charged attraction between curved surfaces and formulation of a hydrogen bonding style mechanism

AIP Advances, 2013
For the first time, the classical density functional theory (DFT) is numerically solved in three- and two-dimensional spaces for a two sphere model of electrostatic interactions between two spherical nanoscale colloids immersed in a primitive model ...
Shiqi Zhou
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

STUDI MEKANISME KINETIKA REAKSI PERTUKARAN ION FE(III) ANTARA DUA JENIS LIGAN SIDEROPHORE BAKTERI (DESFERRIFERRIOXAMINE B DAN AZOVERDINE) DENGAN LIGAN EDTA

Journal of Biological Researches, 2014
The kinetics of iron exchange and iron removal from two siderophore complex with use of ethylenediaminetetraacetic acid (EDTA) have been examined, using UV-Vis spectrophotometric method.
Handoko Darmokoesoemo, A.M. Albrecht Gary   +1 more
doaj  

Impact of ICRH resonant layer position on core plasma performances in WEST H-minority plasmas

Nuclear Fusion
A systematic experimental study of hydrogen-minority ion cyclotron resonance heating (ICRH) has been performed in deuterium plasmas in WEST to optimize the power deposition.
S. Mazzi, J. Morales, E. Lerche, L. Colas, J. Hillairet, H. Corvoysier, R. Dumont, N. Fedorczak, J. Garcia, Ph. Huynh, P. Puglia, P. Maget, P. Manas, F. Orlacchio, R. Ragona, G. Urbanczyk, L. Vermare, the WEST Team   +17 more
doaj   +1 more source

Twenty-four-hour pH monitoring of gastric conduit in post-esophagectomy patients: correlation with clinical and endoscopic parameters in a prospective cohort study from India

Journal of Minimally Invasive Surgery
Purpose: Esophagectomy for malignancy leads to decreased gastric conduit acidity due to bilateral vagotomy and fundic gland area reduction. However, reflux symptoms occur.
Vishu Jain, Vaibhav Kumar Varshney, Subhash Chandra Soni, B Selvakumar, Peeyush Varshney, Lokesh Agarwal, Ashish Agarwal, Chhagan Lal Birda   +7 more
doaj   +1 more source

Karl Popper and the Mechanisms of Hydrogen Embrittlement

Advanced Engineering Materials, EarlyView.
Representation of the beginning of loss of ductility rather than embrittlement. Small concentrations of hydrogen in a diffusible form within iron are well‐established to harm the mechanical integrity of steels. There are theories that attempt to explain the pernicious role of hydrogen.
H. K. D. H. Bhadeshia
wiley   +1 more source

Generation of hydrogen ionic plasma superimposed with positive ion beam

AIP Advances, 2019
In this study, a hydrogen ionic plasma with relatively low residual fractional electron concentration (ne/n+ ∼ 10−2) is generated using an aluminum plasma grid for the production of negative hydrogen ions and a control grid for negative ion extraction ...
W. Oohara, M. Fujii, M. Watai, Y. Hiraoka, M. Egawa, Y. Morinaga, S. Takamori, M. Yoshida   +7 more
doaj   +1 more source