Results 31 to 40 of about 4,500,986 (299)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The Effect of Nickel Plating on Hydrogen Embrittlement of High Strength Steel. [PDF]

, 1992
The microstructure of high strength steel is susceptible to delayed failure caused by the absorption of hydrogen produced either during cathodic charging or electroplating. When 0.8%C and AISI 4340 steel are subjected to constant load testing, a wide
Evans, Juliet M.
core   +6 more sources

Energy-efficient modular water purification system via concurrent freshwater and hydrogen generation using ion concentration polarization

Communications Materials
This study demonstrates a compact, modular platform that simultaneously generates freshwater and hydrogen gas by leveraging nanoelectrokinetic ion concentration polarization through cation-exchange membranes (CEMs).
Jihee Park, Sehyuk Yoon, Myeonghyeon Cho, Dongguen Eom, Beomjoon Kim, Hyomin Lee, Wonseok Kim, Sangwook Park, Sungjae Ha, Sung Jae Kim   +9 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Generation of quasi-monoenergetic protons from thin multi-ion foils by a combination of laser radiation pressure acceleration and shielded Coulomb repulsion

New Journal of Physics, 2013
We study theoretically and numerically the acceleration of protons by a combination of laser radiation pressure acceleration and Coulomb repulsion of carbon ions in a multi-ion thin foil made of carbon and hydrogen.
Tung-Chang Liu, Xi Shao, Chuan-Sheng Liu, Minqing He, Bengt Eliasson, Vipin Tripathi, Jao-Jang Su, Jyhpyng Wang, Shih-Hung Chen   +8 more
doaj   +1 more source

pH and calcium ion release evaluation of pure and calcium hydroxide-containing Epiphany for use in retrograde filling

Journal of Applied Oral Science, 2011
OBJECTIVE: Hydroxyl (OH-) and calcium (Ca++) ion release was evaluated in six materials: G1) Sealer 26, G2) White mineral trioxide aggregate (MTA), G3) Epiphany, G4) Epiphany + 10% calcium hydroxide (CH), G5) Epiphany + 20% CH, and G6) zinc oxide and ...
Mário Tanomaru-Filho, Juliana Nogueira Saçaki, Frederico Bordini Chaves Faleiros, Juliane Maria Guerreiro-Tanomaru   +3 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

A performance comparison of photo-fenton decolorization of methylene blue by using bentonite/iron composites prepared by liquid phase and solid phase ion exchange method

Desalination and Water Treatment
Nowadays, there is a wide range of pollutants present, which requires the treatment of wastewater. The photo-Fenton method has been recognized as valuable in this area.
Mohammed Jaafar Ali Alatabe, Mohammad Ghorbanpour   +1 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source