Results 21 to 30 of about 289,732 (268)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Energy-efficient modular water purification system via concurrent freshwater and hydrogen generation using ion concentration polarization

open access: yesCommunications Materials
This study demonstrates a compact, modular platform that simultaneously generates freshwater and hydrogen gas by leveraging nanoelectrokinetic ion concentration polarization through cation-exchange membranes (CEMs).
Jihee Park   +9 more
doaj   +1 more source

pH and calcium ion release evaluation of pure and calcium hydroxide-containing Epiphany for use in retrograde filling

open access: yesJournal of Applied Oral Science, 2011
OBJECTIVE: Hydroxyl (OH-) and calcium (Ca++) ion release was evaluated in six materials: G1) Sealer 26, G2) White mineral trioxide aggregate (MTA), G3) Epiphany, G4) Epiphany + 10% calcium hydroxide (CH), G5) Epiphany + 20% CH, and G6) zinc oxide and ...
Mário Tanomaru-Filho   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Generation of quasi-monoenergetic protons from thin multi-ion foils by a combination of laser radiation pressure acceleration and shielded Coulomb repulsion

open access: yesNew Journal of Physics, 2013
We study theoretically and numerically the acceleration of protons by a combination of laser radiation pressure acceleration and Coulomb repulsion of carbon ions in a multi-ion thin foil made of carbon and hydrogen.
Tung-Chang Liu   +8 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A performance comparison of photo-fenton decolorization of methylene blue by using bentonite/iron composites prepared by liquid phase and solid phase ion exchange method

open access: yesDesalination and Water Treatment
Nowadays, there is a wide range of pollutants present, which requires the treatment of wastewater. The photo-Fenton method has been recognized as valuable in this area.
Mohammed Jaafar Ali Alatabe   +1 more
doaj   +1 more source

Water sorption and solubility of glass ionomer cements indicated for atraumatic restorative treatment considering the time and the pH of the storage solution

open access: yesRGO: Revista Gaúcha de Odontologia, 2018
Objective: Evaluate the water sorption and the solubility of glass ionomer cements considering the time and the pH of the storage solution. Methods: The materials used in this survey study were the following ones: Ketac Molar Easymix, Maxxion R, Vitro ...
Renally Bezerra Wanderley e LIMA   +4 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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