Results 61 to 70 of about 7,269,256 (239)

HYDROGEN ADDITION ON COMBUSTION AND EMISSION CHARACTERISTICS OF HIGH SPEED SPARK IGNITION ENGINE- AN EXPERIMENTAL STUDY [PDF]

Journal of Engineering Science and Technology, 2016
The present article aims at characterizing the combustion and emission parameters of a single cylinder high speed SI engine operating with different concentrations of hydrogen with gasoline fuel.
SHIVAPRASAD K. V. , P. R. CHITRAGAR, KUMAR G. N.   +2 more
doaj  

Experimental Study on Zn-Doped Al-Rich Alloys for Fast on-Board Hydrogen Production

Crystals, 2020
For the purpose of investigating the effect of Zn replacement of In3Sn on the hydrogen production performance of Al-rich alloy ingots, Al-Ga-In3Sn alloys with various Zn dosages (0−5 wt.%) were prepared by a traditional melting and casting ...
Dan Liu, Qian Gao, Qi An, Hongchao Wang, Jilun Wei, Cundi Wei   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Influences of hydrogen addition from different dual‐fuel modes on engine behaviors

Energy Science & Engineering, 2022
Compression ignition (CI) engines have good performance but more exhaust emissions. Dual fuel (DF) engines have better performance and lower emissions compared to CI mode.
Sanjeevakumar Veerasangappa Khandal, Ümit Ağbulut, Asif Afzal, Mohsen Sharifpur, Kaladgi Abdul Razak, Nima Khalilpoor   +5 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

New hydrogen-bonding organocatalysts: Chiral cyclophosphazanes and phosphorus amides as catalysts for asymmetric Michael additions

Beilstein Journal of Organic Chemistry, 2014
Ten novel hydrogen-bonding catalysts based on open-chain PV-amides of BINOL and chinchona alkaloids as well as three catalysts based on rigid cis-PV-cyclodiphosphazane amides of N1,N1-dimethylcyclohexane-1,2-diamine have been developed.
Helge Klare, Jörg M. Neudörfl, Bernd Goldfuss   +2 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Enhancing Diesel Engine Performance Through Hydrogen Addition

Fire
This study evaluates the potential of hydrogen as a clean additive to conventional diesel fuel. Experiments were carried out on a single-cylinder, air-cooled diesel engine under half- and full-load conditions, across engine speeds ranging from 1000 to ...
Sahbi Ben Abdelwahed, Fakher Hamdi, Mehrez Gassoumi, Ilham Yahya, Noomen Moussa, Nashmi H. Alrasheedi, Ridha Ennetta, Borhen Louhichi   +7 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source