Results 61 to 70 of about 1,754,714 (305)

Pulsations powered by hydrogen shell burning in white dwarfs [PDF]

open access: yes, 2016
In the absence of a third dredge-up episode during the asymptotic giant branch phase, white dwarf models evolved from low-metallicity progenitors have a thick hydrogen envelope, which makes hydrogen shell burning be the most important energy source.
Althaus, Leandro G.   +3 more
core   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Muonic hydrogen cascade time and lifetime of the short-lived $2S$ state [PDF]

open access: yes, 2006
Metastable ${2S}$ muonic-hydrogen atoms undergo collisional ${2S}$-quenching, with rates which depend strongly on whether the $\mu p$ kinetic energy is above or below the ${2S}\to {2P}$ energy threshold.
A. Antognini   +33 more
core   +4 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Influences of hydrogen addition from different dual‐fuel modes on engine behaviors

open access: yesEnergy Science & Engineering, 2022
Compression ignition (CI) engines have good performance but more exhaust emissions. Dual fuel (DF) engines have better performance and lower emissions compared to CI mode.
Sanjeevakumar Veerasangappa Khandal   +5 more
doaj   +1 more source

The Effect of the Environment on alpha-Al_2O_3 (0001) Surface Structures

open access: yes, 2000
We report that calculating the Gibbs free energy of the alpha-Al_2O_3 (0001) surfaces in equilibrium with a realistic environment containing both oxygen and hydrogen species is essential for obtaining theoretical predictions consistent with experimental ...
Anne Chaka   +18 more
core   +1 more source

Understanding adsorption of hydrogen atoms on graphene [PDF]

open access: yes, 2008
Adsorption of hydrogen atoms on a single graphite sheet (graphene) has been investigated by first-principles electronic structure means, employing plane-wave based, periodic density functional theory.
Cooper D. L.   +6 more
core   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Home - About - Disclaimer - Privacy