Results 41 to 50 of about 636,871 (343)

8-[(1E)-1-(2-Aminophenyliminio)ethyl]-2-oxo-2H-chromen-7-olate

Acta Crystallographica Section E, 2010
The title Schiff base, C17H14N2O3, exists as an NH tautomer with the H atom of the phenol group transferred to the imine N atom. The iminium H atom is involved in a strong intramolecular N+—H...O− hydrogen bond to the phenolate O atom,
E. S. Aazam, A. F. El Husseiny, H. M. Al-Amri, Orhan Büyükgüngör   +3 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Noncommutative Coulombic Monopole

, 2005
We have constructed the appropriate Hamiltonian of the noncommutative coulombic monopole (i.e. the noncommutative hydrogen atom with a monopole). The energy levels of this system have been calculated, discussed and compared with the noncommutative ...
Armen Yeranyan, D. A. Varshalovich, E. Witten, L. D. Landau, Stefano Bellucci   +4 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

(Z)-2-(2-Isopropyl-5-methylphenoxy)-N′-(2-oxoindolin-3-ylidene)acetohydrazide

Acta Crystallographica Section E, 2010
In the title Mannich base, C20H21N3O3, an isatin derivative of thymol, the O—CH2—C(=O)–N(H)—N fragment connecting the aromatic and fused-ring systems is approximately planar, with the N—N single bond in a
Chetan M. Zade, Umesh D. Pete, Amol G. Dikundwar, Ratnamala S. Bendre   +3 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

1-(5,7-Dihydroxy-2,2-dimethylchroman-6-yl)ethanone

Acta Crystallographica Section E, 2011
In the title molecule, C13H16O4, the pyran ring is in a half-chair conformation. There is an intramolecular hydrogen bond involving the ketone O atom and an H atom of a phenol group which forms an S(6) ring.
Matthew P. Akerman, Zimbili Mkhize, Fanie R. van Heerden   +2 more
doaj   +1 more source

Semi-classical analysis of real atomic spectra beyond Gutzwiller's approximation

, 2005
Real atomic systems, like the hydrogen atom in a magnetic field or the helium atom, whose classical dynamics are chaotic, generally present both discrete and continuous symmetries.
Benoît Grémaud, D. Delande, E. P. Bogomolny, E. P. Bogomolny, K. Weibert, L. S. Schulmann, M. C. Gutzwiller   +6 more
core   +1 more source

Titan’s atomic hydrogen corona [PDF]

Icarus, 2010
Abstract Based on measurements performed by the Hydrogen Deuterium Absorption Cell (HDAC) aboard the Cassini orbiter, Titan’s atomic hydrogen exosphere is investigated. Data obtained during the T9 encounter are used to infer the distribution of atomic hydrogen throughout Titan’s exosphere, as well as the exospheric temperature.
Hedelt, P., Ito, Y., Keller, H.U., Reulke, R., Wurz, P., Lammer, H., Rauer, H., Esposito, L.   +7 more
openaire   +3 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source