Results 91 to 100 of about 1,847,339 (304)

Low-concentrated nonvital bleaching effect on bond strength of composite resin restorations

open access: yesBrazilian Dental Science, 2016
Objective: To investigate if short-term dentin bleaching with low-concentrated substances affects the bond strength of immediate resin composite restorations.
Fabiana Gomes Néspoli   +5 more
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

How ammonia participates in hydrogen bonding

open access: yes, 2007
High resolution spectral data on molecular complexes observed in free jet expansions and in particular rotationally resolved spectra, provide a wealth of information on the structure and the detailed nature of non-covalent interactions.
MELANDRI, SONIA   +5 more
core   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Strength of hydrogen bond network takes crucial roles in the dissociation process of inhibitors from the HIV-1 protease binding pocket.

open access: yesPLoS ONE, 2011
To understand the underlying mechanisms of significant differences in dissociation rate constant among different inhibitors for HIV-1 protease, we performed steered molecular dynamics (SMD) simulations to analyze the entire dissociation processes of ...
Dechang Li   +3 more
doaj   +1 more source

Hydrogen-Bond-Driven Core-Crosslinked Supramolecular Micelles with pH/Thermal/Glutathione-Responsive Drug Release toward Enhanced Cancer Therapy

open access: yes, 2023
The field of anticancer nanomedicine seeks to boost the arsenal’s exploitation with intelligent performance. One opportunistic choice comes from the fabrication of amphiphilic polymer micelles that are reversibly crosslinked. Here, hydrogen-bond (H-bond)-
Yanggui Wu (13803548)   +5 more
core   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

1-(3-Chlorophenyl)-3-(2,6-dichlorobenzoyl)thiourea [PDF]

open access: yes, 2009
The structure of the title compound, C14H9Cl3N2OS, is composed of discrete molecules with bond lengths and angles quite typical for thiourea compounds of this class. The plane containing the thiocarbonyl and carbonyl groups subtends dihedral angles of 48.
Bolte, Michael   +5 more
core   +1 more source

Hydrogen-Bond Network Promotes Water Splitting on the TiO2 Surface

open access: yes, 2022
Breaking the strong covalent O–H bond of an isolated H2O molecule is difficult, but it can be largely facilitated when the H2O molecule is connected with others through hydrogen-bonding.
Xiaochuan Ma (1699969)   +7 more
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

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