Results 111 to 120 of about 3,073,614 (389)

Primary Human Tissue Models for Metabolic Dysfunction‐Associated Liver Disease ‐ toward Streamlining Drug Discovery with Patient‐Derived Assays

open access: yesAdvanced Biology, EarlyView.
The review provides a critical up‐to‐date overview of the current landscape of human in vitro models for fatty liver disease, including spheroids, organoids, organ‐on‐a‐chip systems, bioprinted liver constructs and precision‐cut liver slices. Their utility for faithfully modeling different stages of MASLD and MASH are evaluated and their compatibility ...
Sonia Youhanna   +6 more
wiley   +1 more source

Conformational analysis and intramolecular interactions in monosubstituted phenylboranes and phenylboronic acids

open access: yesBeilstein Journal of Organic Chemistry, 2013
A 1TSJF,H(O) coupling pathway, dictated by a hydrogen bond, in some 2-fluorobenzoic acids has been observed, while such an interaction does not occur in 2-fluorophenol. Thus, this work reports the conformational analysis of 2-fluorophenylboronic acid (1),
Josué M. Silla   +3 more
doaj   +1 more source

Differentiation Treatment Applied to Lung Cancer Model Reduces Pathogenic Traits in Vitro

open access: yesAdvanced Biology, EarlyView.
Non‐small cell lung cancer cells (A549) treated with a differentiation medium showed strong reduction in proliferation, migration, clonogenicity, spheroid formation and stemness markers, with enhanced adhesion properties and alveolar features, all pointing to a notably less aggressive phenotype in support of differentiation therapy as a promising ...
Alice Grossi   +10 more
wiley   +1 more source

2-{[(Pyridin-2-yl)amino]methyl}phenol

open access: yesActa Crystallographica Section E, 2012
The planes of the aromatic rings of the title compound, C12H12N2O, are twisted by 50.33 (15)°. The phenol O atom is a hydrogen-bond donor to the pyridine N atom, resulting in the formation of an eight-membered ring in the molecule. The
Shan Gao, Seik Weng Ng
doaj   +1 more source

Direct observation of ultrafast hydrogen bond strengthening in liquid water

open access: yesNature, 2021
Jie Yang   +21 more
semanticscholar   +1 more source

Osteogenic Effects of Ion Released from Biodegradable Metallic Magnesium and Calcium Coating

open access: yesAdvanced Biology, EarlyView.
This study explores how magnesium–calcium coatings on titanium promote osteogenesis by releasing ions and elevating pH during degradation. Using osteoblast‐like cells, the research demonstrates that both ion release and pH changes contribute to cell proliferation, differentiation, and mineralization, offering new insights into the design of bioactive ...
Risa Miyake   +4 more
wiley   +1 more source

2-Methyl-N-[(3-methyl-2-pyridyl)carbamothioyl]benzamide

open access: yesActa Crystallographica Section E, 2008
In the title compound, C15H15N3OS, the thiourea group is stabilized by an intramolecular hydrogen bond between the carbonyl O atom and the thioamide group. A C—H...N intramolecular hydrogen bond is also present.
R. H. Jusoh   +3 more
doaj   +1 more source

Development of Aluminum Scandium Alloys for Hydrogen Storage Valves

open access: yesAdvanced Engineering Materials, EarlyView.
Different aluminum alloy series and various aluminum‐scandium alloys with differing Sc and Zr levels are evaluated for use in hydrogen storage valve production. The alloys undergo hardness testing, optical microscopy, and tensile strength analysis, with hardening behavior studied under varying conditions.
Francisco García‐Moreno   +4 more
wiley   +1 more source

4-Hydroxy-1-oxo-1,2-dihydrophthalazine-6,7-dicarboxylic acid dihydrate

open access: yesActa Crystallographica Section E, 2008
In the crystal structure of the title compound, C10H6N2O6·2H2O, the OH and NH groups each serve as a hydrogen-bond donor to one acceptor site whereas the water molecules each serve as a hydrogen-bond donor to two acceptor sites. The hydrogen-bonding
Ling-Ling Liang   +2 more
doaj   +1 more source

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