Results 31 to 40 of about 2,615,661 (354)
Frontiers in Plant Science, 2023 In photosystem II (PSII), the O3 and O4 sites of the Mn4CaO5 cluster form hydrogen bonds with D1-His337 and a water molecule (W539), respectively. The low-dose X-ray structure shows that these hydrogen bond distances differ between the two homogeneous ...
Keisuke Saito +4 more
doaj +1 more source
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
On the Hydrogen Bond Strength and Vibrational Spectroscopy of Liquid Water
Scientific Reports, 2018 In the present work, we introduce two new metrics i.e. hydrogen-bond strength and charge-transfer between the donor/acceptor water molecules as a measure of hydrogen-bond rearrangement dynamics. Further, we also employ a simple model based on energy flux
D. Ojha, K. Karhan, T. Kühne
semanticscholar +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
2-[(4-Methylbenzoyl)hydrazono]propionic acid monohydrate
Acta Crystallographica Section E, 2009 In the title compound, C11H12N2O3·H2O, the water molecule is a hydrogen-bond donor to the double-bond amide and the carbonyl O atoms of two acid molecules; it is also a hydrogen-bond acceptor to the acid –OH and amide –NH– groups ...
Seik Weng Ng, Kong Mun Lo, Hon Wee Wong
doaj +1 more source
Regulation of protein-ligand binding affinity by hydrogen bond pairing
Science Advances, 2016 Receptor-ligand H-bond pairings have evolved to promote high-affinity binding by reducing competitive interference with water. Hydrogen (H)-bonds potentiate diverse cellular functions by facilitating molecular interactions.
Deliang Chen +5 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Methyl 2-amino-4,5-dimethoxybenzoate
Acta Crystallographica Section E, 2013 The title compound, C10H13NO4, is essentially planar, with an r.m.s. deviation of 0.049 Å. An intramolecular C—H...O hydrogen bond occurs and the amino group forms an intramolecular N—H...Oester hydrogen bond; the other H atom ...
Naadiya Patel, Tania N. Hill
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2013 Activation of the C–F bond of benzylic fluorides was achieved using 1,1,1-tris(hydroxymethyl)propane (2) as a hydrogen bond-donating agent. Investigations demonstrated that hydrogen bond-donating solvents are promoting the activation and hydrogen bond ...
Pier Alexandre Champagne +3 more
doaj +1 more source