Results 41 to 50 of about 1,847,339 (304)
Hydrogen-Bond-Assisted Symmetry Breaking in a Network of Chiral Metal-Organic Assemblies. [PDF]
, 2019 Herein we elucidate the interplay of chiral, chelate, solvent, and hydrogen-bonding information in the self-assembly of a series of new three-dimensional metal-organic architectures.
Patrick Pröhm (6239552) +4 more
core +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 2022 Publisher Copyright: © 2022 Proceedings of WHEC 2022 - 23rd World Hydrogen Energy Conference: Bridging Continents by H2. All rights reserved.This work addresses the potential of hydrogen injection into the transmission high pressure natural gas grid as ...
Madina, Virginia +5 more
core +1 more source
Beilstein Journal of Organic Chemistry, 2013 Activation of the C–F bond of benzylic fluorides was achieved using 1,1,1-tris(hydroxymethyl)propane (2) as a hydrogen bond-donating agent. Investigations demonstrated that hydrogen bond-donating solvents are promoting the activation and hydrogen bond ...
Pier Alexandre Champagne +3 more
doaj +1 more source
Methyl 2-amino-4,5-dimethoxybenzoate
Acta Crystallographica Section E, 2013 The title compound, C10H13NO4, is essentially planar, with an r.m.s. deviation of 0.049 Å. An intramolecular C—H...O hydrogen bond occurs and the amino group forms an intramolecular N—H...Oester hydrogen bond; the other H atom ...
Naadiya Patel, Tania N. Hill
doaj +1 more source
Frontiers in Plant Science, 2023 In photosystem II (PSII), the O3 and O4 sites of the Mn4CaO5 cluster form hydrogen bonds with D1-His337 and a water molecule (W539), respectively. The low-dose X-ray structure shows that these hydrogen bond distances differ between the two homogeneous ...
Keisuke Saito +4 more
doaj +1 more source
A model for the hydrogen bond [PDF]
Proceedings of the National Academy of Sciences, 1975 A model of the linear hydrogen bond has been devised which is characterized by three physical parameters of the isolated electron donor and proton donor molecules: μ A-H , the bond dipole moment; Δ I , the difference in ionization potential between that
openaire +2 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
The Characteristics of PD-L1 Inhibitors, from Peptides to Small Molecules
Molecules, 2019 The programmed cell death ligand protein 1 (PD-L1) is a member of the B7 protein family and consists of 290 amino acid residues. The blockade of the PD-1/PD-L1 immune checkpoint pathway is effective in tumor treatment.
Yanwen Zhong +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source