Results 61 to 70 of about 1,847,339 (304)

Hydrogen bonding in organic systems: a study using x-ray and neutron diffraction and database analyses. [PDF]

open access: yes, 1999
This thesis covers three topics related to the field of crystal engineering. Three different approaches to improving the understanding of hydrogen bonding are covered; analysis of a family of related molecules, investigations of specific functional ...
Bilton, Clair
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Effect of the Hydration Shell on the Carbonyl Vibration in the Ala-Leu-Ala-Leu Peptide

open access: yesMolecules, 2021
The vibrational spectrum of the Ala-Leu-Ala-Leu peptide in solution, computed from first-principles simulations, shows a prominent band in the amide I region that is assigned to stretching of carbonyl groups.
Irtaza Hassan   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Hydrogen-Bond-Induced Emission of Carbon Dots for Wash-Free Nucleus Imaging

open access: yes, 2019
Carbon dots (CDs) are emerging as powerful tools for biosensing and bioimaging because of their intrinsic properties such as abundant precursors, facile synthesis, high biocompatibility, low cost, and particularly robust tunability and stability. In this
Xiaobing Zhang (12137)   +10 more
core   +1 more source

High‐Performance Polymeric Materials through Hydrogen‐Bond Cross‐Linking

open access: yes, 2020
It has always been critical to develop high‐performance polymeric materials with exceptional mechanical strength and toughness, thermal stability, and even healable properties for meeting performance requirements in industry.
Pingan Song   +3 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Mechanism of deep eutectic solvent on coal spontaneous combustion

open access: yesMeitan xuebao
Chemical inhibition is one of the important measures for the prevention and control of coal spontaneous combustion. This paper proposed a quasi-ionic liquid inhibition method based on deep eutectic solvents (DES).
Xuyao QI   +5 more
doaj   +1 more source

(2E)-2-(3-Ethoxy-2-hydroxybenzylidene)hydrazinecarboxamide

open access: yesActa Crystallographica Section E, 2013
The title compound, C10H13N3O3, adopts an E conformation with respect to the azomethine bond and crystallizes in the amide form. A classical intramolecular O—H...N hydrogen bond is present.
A. Ambili Aravindakshan   +2 more
doaj   +1 more source

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