Results 51 to 60 of about 584,997 (254)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

1H-NMR and viscosity studies of hydrogen bonding of Chinese rice wine

open access: yesCyTA - Journal of Food, 2018
The viscosity of Chinese rice wine gradually increases with the maturing process, resulting in a better taste due to longer contact with the tongue. Herein, the structure of water–ethanol was detected by hydrogen nuclear magnetic resonance (1H-NMR) and ...
Jingjing Cao   +5 more
doaj   +1 more source

Modulation of the Selectivity in Anions Recognition Processes by Combining Hydrogen- and Halogen-Bonding Interactions

open access: yesMolecules, 2017
Most of the halogen bonding receptors for anions described use halogen bonding binding sites solely in the anion recognition process; only a few examples report the study of anion receptors in which the halogen bonding interaction has been used in ...
Fabiola Zapata   +4 more
doaj   +1 more source

Tris(hydroxypropyl)phosphine Oxide: A Chiral Three-Dimensional Material with Nonlinear Optical Properties [PDF]

open access: yes, 2010
The achiral C_(3v) organic phosphine tris(hydroxypropyl)phosphine oxide (1) crystallizes in the unusual chiral hexagonal space group P6_3. The structure is highly ordered because each phosphine oxide moiety forms three hydrogen bonds with adjacent ...
Durrell, Alec C.   +5 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Interactions of Re and hydrogen at γ/γ′ interfaces enhanced hydrogen-embrittlement resistance of Re-optimized Ni-based superalloy

open access: yesMaterials Research Letters
This work elucidates the interactions between Re and hydrogen at γ/γ′ interfaces, enhancing the hydrogen-embrittlement resistance of nickel-based single-crystal superalloy (Ni-SX).
Yunsong Zhao   +7 more
doaj   +1 more source

Bonding-Based Wafer-Level Vacuum Packaging Using Atomic Hydrogen Pre-Treated Cu Bonding Frames

open access: yesMicromachines, 2018
A novel surface activation technology for Cu-Cu bonding-based wafer-level vacuum packaging using hot-wire-generated atomic hydrogen treatment was developed.
Koki Tanaka   +4 more
doaj   +1 more source

Spectroscopic studies of the mechanism for hydrogen-induced exfoliation of InP [PDF]

open access: yes, 2005
The motion and bonding configurations of hydrogen in InP are studied after proton implantation and subsequent annealing, using Fourier transform infrared (FTIR) spectroscopy. It is demonstrated that, as implanted, hydrogen is distributed predominantly in
Atwater, Harry A.   +4 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Hydrogen bonding characterization in water and small molecules

open access: yes, 2017
The prototypical Hydrogen bond in water dimer and Hydrogen bonds in the protonated water dimer, in other small molecules, in water cyclic clusters, and in ice, covering a wide range of bond strengths, are theoretically investigated by first-principles ...
Silvestrelli, Pier Luigi
core   +1 more source

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