The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Atmospheric Impacts of Hydrogen as an Energy Carrier [PDF]
Hydrogen gas emissions to the atmosphere can very likely cause global warming through indirect effects. It can also possibly cause depletion of the ozone layer, and impact air pollution.
Sandstad, Marit +3 more
core
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Carrier-Selective Blocking Layer Synergistically Improves the Plasmonic Enhancement Effect [PDF]
Plasmonic enhancement is a versatile and convenient way to enhance the conversion efficiency of various photoenergy conversion systems, such as photocatalysts and solar cells.
Toshiharu Teranishi +7 more
core +1 more source
Investigating the Aging Behavior of High-Density Polyethylene and Polyketone in a Liquid Organic Hydrogen Carrier. [PDF]
Surisetty J +3 more
europepmc +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
On the Way to Utilizing Green Hydrogen as an Energy Carrier—A Case of Northern Sweden [PDF]
Low or even zero carbon dioxide emissions will be an essential requirement for energy supplies in the near future. Besides transport and electricity generation, industry is another large carbon emitter.
Bollen, Math H. J., +6 more
core +1 more source
The Suppressor of AAC2 Lethality SAL1 Modulates Sensitivity of Heterologously Expressed Artemia ADP/ATP Carrier to Bongkrekate in Yeast [PDF]
The ADP/ATP carrier protein (AAC) expressed in Artemia franciscana is refractory to bongkrekate. We generated two strains of Saccharomyces cerevisiae where AAC1 and AAC3 were inactivated and the AAC2 isoform was replaced with Artemia AAC containing a ...
Adam-Vizi, Vera +48 more
core +1 more source
Energy systems design is challenged by uncertainties in energy carrier costs. This study explores hydrogen and conventional energy carrier costs, providing global insights with a focus on Belgium.
Jordi F. P. Cornette, Julien Blondeau
doaj +1 more source

