Results 41 to 50 of about 197,550 (311)
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Technical indicators of ammonia heavy duty engines
This article presents a literature review of the use of ammonia in combination with diesel fuel to power heavy duty engines. The main advantages and disadvantages in using ammonia as a fuel are shown.
Dawid Mielcarzewicz
doaj +1 more source
As shown in the previous articles of this series, hydrogen is the most suitable choice as a substitution for helium as a carrier gas in gas chromatography.
Tomáš HORÁK +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Threats and Challenges Associated with Ammonia Transport via Pipeline Systems
Ammonia, due to its favorable physicochemical properties, is considered an effective hydrogen carrier, enabling the storage of surplus energy generated from renewable sources.
Tomasz Kuchta +3 more
doaj +1 more source
Hydrogen as a clean energy carrier has attracted great interests world-wide for substitution of fossil fuels and for abatement of the climate change concerns.
Shusheng Pang
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Use of a 3D Workpiece to Inductively Heat an Ammonia Cracking Reactor
Ammonia, widely regarded as the “hydrogen carrier of the future,” offers high hydrogen content, ease of production, and a well-established infrastructure for handling and transportation globally. Meanwhile, ammonia cracking requires a heat supply at high
Debora de Figueiredo Luiz +3 more
doaj +1 more source
Gas chromatography often uses helium, hydrogen, and nitrogen as carrier gases. The most common carrier gas is helium since it provides good separations, is inert, and is safe to use.
Tomáš HORÁK +3 more
doaj +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source

