Results 91 to 100 of about 219,729 (312)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Hydrogen Production Using Electrodeposited Ni and Ni/Co on Carbon Paper as Cathode Catalyst in Microbial Electrolysis Cells

International Journal of Electrochemical Science, 2018
Microbial electrolysis cells (MECs) utilize microorganisms to decompose organic matter in wastewater and produce hydrogen at the cathode. Thus, a low-cost and highly active cathode material is of great important in such system.
Yuxue Wang, Yu Zhao, Ailian Wu, Zhishuai Dong, Jia Li, Junwen Wang   +5 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Facile Synthesis of Well-Dispersed Ni₂P on N-Doped Nanomesh Carbon Matrix as a High-Efficiency Electrocatalyst for Alkaline Hydrogen Evolution Reaction

Nanomaterials, 2019
The development of non-noble metal hydrogen evolution catalysts that can replace Pt is crucial for efficient hydrogen production. Herein, we develop a type of well-dispersed Ni2P on N-doped nanomesh carbon (NC) electrocatalyst by a facile pyrolysis ...
Fan Yang, Shuo Huang, Bing Zhang, Liqiang Hou, Yi Ding, Weijie Bao, Chunming Xu, Wang Yang, Yongfeng Li   +8 more
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Arenas of Expectations for Hydrogen Technologies [PDF]

Technological options can be regarded as variations in an evolutionary development process. The variations are put forward by their respective technological communities and are selected by technology selectors.
Harro van Lente, Sjoerd Bakker, Marius Meeus   +2 more
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Enhanced Photocatalytic Hydrogen Evolution Activity Driven by the Synergy Between Surface Vacancies and Cocatalysts: Surface Reaction Matters

Advanced Science
The incorporation of defects and cocatalysts is known to be effective in improving photocatalytic activity, yet their coupled contribution to the photocatalytic hydrogen evolution process has not been well‐explored. In this study, We demonstrate that the
Wenhui Yue, Ziwei Ye, Cong Liu, Zehong Xu, Lingzhi Wang, Xiaoming Cao, Hiromi Yamashita, Jinlong Zhang   +7 more
doaj   +1 more source

Why do sulfone-containing polymer photocatalysts work so well for sacrificial hydrogen evolution from water?

, 2022
In recent years, many of the highest performing polymer photocatalysts for hydrogen evolution from water have contained dibenzo[b,d]thiophene sulfone units in their polymer backbones.
Drew, Pearce, Wai-Yu, Sit, Reiner Sebastian , Sprick, Sam A. J., Hillman, Jenny, Nelson, Andrew I., Cooper, James R., Durrant, Xingyuan, Shi, Duncan, Woods   +8 more
core   +1 more source