Results 111 to 120 of about 4,584,056 (379)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Ambient temperature catalyst for hydrogen ignition [PDF]

open access: yes, 1968
Low cost, ambient temperature catalyst for reacting hydrogen gas with air in a catalytic cell near the point of evolution at a controlled rate is ...
Roberts, R. W.
core   +1 more source

Hydrogen evolution from silicon nanowire surfaces

open access: yesRSC Advances, 2018
This paper presents the study on the hydrogen evolution reaction (HER) of the silicon nanowire (SiNW)-based surfaces.
Rui Feng   +9 more
openaire   +3 more sources

YFeO3 Photocathodes for Hydrogen Evolution [PDF]

open access: yesElectrochimica Acta, 2017
VC gratefully acknowledges the Royal Society and the UK National Academy by the support through the Newton International Fellows program and EPSRC via the UK Catalysis Hub (EP/K014706/1 and EP014714/1). DT and DJF is grateful to EPSRC for funding through the PVTEAM Programme (EP/L017792/1), as well as to the Institute of Advanced Studies of the ...
Dã­ez garcã­a, Marã­a Isabel   +5 more
openaire   +5 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Efficient and stable visible-light-driven Z-scheme overall water splitting using an oxysulfide H2 evolution photocatalyst

open access: yesNature Communications
So-called Z-scheme systems permit overall water splitting using narrow-bandgap photocatalysts. To boost the performance of such systems, it is necessary to enhance the intrinsic activities of the hydrogen evolution photocatalyst and oxygen evolution ...
Lihua Lin   +13 more
doaj   +1 more source

Liquid Hydrogen Target Experience at SLAC [PDF]

open access: yes, 2005
Liquid hydrogen targets have played a vital role in the physics program at SLAC for the past 40 years. These targets have ranged from small "beer can" targets to the 1.5 m long E158 target that was capable of absorbing up to 800 W without any significant
/Caltech   +16 more
core   +2 more sources

Hydrogen evolution by strictly aerobic hydrogen bacteria under anaerobic conditions [PDF]

open access: yesJournal of Bacteriology, 1984
When strains and mutants of the strictly aerobic hydrogen-oxidizing bacterium Alcaligenes eutrophus are grown heterotrophically on gluconate or fructose and are subsequently exposed to anaerobic conditions in the presence of the organic substrates, molecular hydrogen is evolved.
M, Kuhn, A, Steinbüchel, H G, Schlegel
openaire   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Home - About - Disclaimer - Privacy