Results 91 to 100 of about 5,299,592 (349)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Palladium based membranes and membrane reactors for hydrogen production and purification:An overview of research activities at Tecnalia and TU/e [PDF]

, 2016
In this paper, the main achievements of several European research projects on Pd based membranes and Pd membrane reactors for hydrogen production are reported.
E. Fernandez, Spallina, V., de Nooijer, N.C.A., A. Arratibel, F. Gallucci, D.A. Pacheco Tanaka, Melendez, J., Gallucci, F., Pacheco Tanaka, D. A., M. van Sint Annaland, Zuniga Palacio, Jon, Zuñiga, J., Fernandez, Ekain, Arratibel, A., Helmi Siasi Farimani, A., V. Spallina, Fernandez, E., Helmi, A., J. Melendez, Medrano Jimenez, J.A., de Nooijer, N. C.A., Coenen, K.T., Pacheco Tanaka, D.A., Melendez Rey, J., Viviente, J. L., J.L. Viviente, Medrano, J. A., van Sint Annaland, M., J. Zuñiga, Gallucci, F.; id_orcid, Coenen, K., K. Coenen, Viviente, J.L., A. Helmi, J.A. Medrano, Spallina, V.; id_orcid, Arratibel Plazaola, A., N.C.A. de Nooijer   +37 more
core   +4 more sources

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

A New Spherical Catalyst For Hydrogen Evolution Reaction

Cumhuriyet Science Journal, 2018
CuFeZn composite catalysts have been prepared on the graphite electrodeby electrochemical deposition as electrocatalytic materials for hydrogenevolution reaction (HER). The etchingprocess was applied on catalysts in caustic solution to leach out zinc and
Murat Farsak
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Navigating Alkaline Hydrogen Evolution Reaction Descriptors for Electrocatalyst Design

International audienceThe quest for efficient green hydrogen production through Alkaline Water Electrolysis (AWE) is a critical aspect of the clean energy transition.
Ogunkunle, Samuel Akinlolu, Wu, Zhenzhen, Mortier, Fabien, Assil Bouzid, Hinsch, Jack Jon, Lei Zhang, Zhang, Lei, Zhu, Yong, Bouzid, Assil, Samuel Bernard, Yun Wang, Yong Zhu, Bernard, Samuel, Wang, Yun, Fabien Mortier, Jack Jon Hinsch, Samuel Akinlolu Ogunkunle, Zhenzhen Wu   +17 more
core   +1 more source

The hydrogen evolution reaction on codeposited Ni-hydrogen storage intermetallic particles in alkaline medium

, 2000
The hydrogen evolution reaction (HER) was studied on Ni-LaNi5 and Ni-MmNi(3.4)Co(0.8)Al(0.8) electrode materials in 1 mol dm(-3) NaOH solution. The steady-state polarization curves and electrochemical impedance spectroscopy experimental data showed a ...
Bocutti, R., Saeki, M. J., Angelo, ACD, Oliveira, CLF, Florentino, A. O.   +4 more
core   +1 more source

An Analysis of the Conceptual and Functional Factors Affecting the Effectiveness of Proton-Exchange Membrane Water Electrolysis

ChemEngineering
Hydrogen has the potential to decarbonize the energy and industrial sectors in the future, mainly if it is generated by water electrolysis. The proton-exchange membrane water electrolysis (PEMWE) system is regarded as a propitious technology to produce ...
Gaydaa AlZohbi
doaj   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source