Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Mechanism of the Photochemical Isomerization and Oxidation of 2-Butenedial: A Theoretical Study
Under tropospheric conditions, 2-butenedial is photochemically removed to produce secondary organic aerosol. Upon solar irradiation in the lower troposphere, the main photochemical products are ketene-enol (a key intermediate product), furanones, and ...
Andrea Maranzana, Glauco Tonachini
doaj +1 more source
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Temperature and Impurity Induced Stabilization of Cubic HfV2 Laves Phase
The stability of cubic HfV2 ( F d 3 ¯ m ) was investigated as a function of temperature as well as interstitially solved oxygen and hydrogen using density functional theory.
Philipp Keuter +3 more
doaj +1 more source
Competition of Intra- and Intermolecular Forces in Anthraquinone and Its Selected Derivatives
Intra- and intermolecular forces competition was investigated in the 9,10-anthraquinone (1) and its derivatives both in vacuo and in the crystalline phase.
Kamil Raczyński +3 more
doaj +1 more source
Spin-dependent Bohm trajectories associated with an electronic transition in hydrogen
The Bohm causal theory of quantum mechanics with spin-dependence is used to determine electron trajectories when a hydrogen atom is subjected to (semi-classical) radiation. The transition between the 1s ground state and the 2p0 state is examined.
Afriat A +19 more
core +1 more source
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
On kaonic hydrogen. Quantum field theoretic and relativistic covariant approach
We study kaonic hydrogen, the bound K^-p state A_(Kp). Within a quantum field theoretic and relativistic covariant approach we derive the energy level displacement of the ground state of kaonic hydrogen in terms of the amplitude of K^-p scattering for ...
) +51 more
core +1 more source
Casimir-Polder shift of ground-state hyperfine Zeeman sublevels of hydrogen isotopes in a micron-sized metallic cavity at finite temperature [PDF]
Davide Iacobacci +2 more
openalex +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source

