Results 51 to 60 of about 741,396 (287)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

The influence of residual oxidizing impurities on the synthesis of graphene by atmospheric pressure chemical vapor deposition

, 2013
The growth of graphene on copper by atmospheric pressure chemical vapor deposition in a system free of pumping equipment is investigated. The emphasis is put on the necessity of hydrogen presence during graphene synthesis and cooling.
Colomer, Jean-François, Felten, Alexandre, Hackens, Benoît, Reckinger, Nicolas, Santos, Cristiane Nascimento   +4 more
core   +1 more source

Green process for adipic acid synthesis: oxidation by hydrogen peroxide in water micromelusions using Benzalkonium Chloride C12-14 surfactant [PDF]

, 2012
Adipic acid was synthesized by the oxidation of cyclohexene using 30% hydrogen peroxide in a microemulsion in the presence of sodium tungstate as catalyst.
Cognet, Patrick, Lesage, Geoffroy, Poux, Martine, Quesada-Peñate, Isariebel   +3 more
core   +3 more sources

Hydrogen Oxidation by Clostridium kluyveri

Journal of Biological Chemistry, 1959
&urn kluyveri were capable of reducing pyridine nucleotides with hydrogen. Subsequent investigations have shown that a heatstable cofactor of undetermined nature present in boiled cell extracts was required (2). Pyridine nucleotide reduction with hydrogen has since been demonstrated in a number of other microorganisms (3-5).
openaire   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Tailored Design of Mesoporous Nanospheres with High Entropic Alloy Sites for Efficient Redox Electrocatalysis

Advanced Science
High Entropy Alloys (HEAs) are a versatile material with unique properties, tailored for various applications. They enable pH‐sensitive electrocatalytic transformations like hydrogen evolution reaction (HER) and hydrogen oxidation reactions (HOR) in ...
Ravi Nandan, Hiroki Nara, Ho Ngoc Nam, Quan Manh Phung, Quynh Phuong Ngo, Jongbeom Na, Joel Henzie, Yusuke Yamauchi   +7 more
doaj   +1 more source

Hydrogen rich gas generator [PDF]

, 1976
A process and apparatus is described for producing a hydrogen rich gas by introducing a liquid hydrocarbon fuel in the form of a spray into a partial oxidation region and mixing with a mixture of steam and air that is preheated by indirect heat exchange ...
Houseman, J.
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Galvanic Hydrogenation Reaction in Metal Oxide

Nature Communications
Abstract Rational reforming of metal oxide has a potential importance to modulate their inherent properties toward appealing characteristics for various applications. Here, we present a detailed fundamental study of the proton migration phenomena between mediums and propose the methodology for an exquisitely controllable metal oxide ...
JunHwa Kwon, Soonsung So, Ki-Yeop Cho, Seungmin Lee, Kiyeon Sim, Subin Kim, Seunghyun Jo, Byeol Kang, Youn-Ki Lee, Hee-Young Park, Jung Tae Lee, Joo-Hyoung Lee, KwangSup Eom, Thomas F. Fuller   +13 more
openaire   +3 more sources