Results 291 to 300 of about 360,534 (337)

Ultrasound‐Assisted H2 Transmitter Enables Hydrogen‐Gene Therapy to Prevent Anesthesia/Surgery‐Induced Cognitive Impairment

open access: yesAdvanced Science, EarlyView.
Postoperative cognitive dysfunction (POCD) remains a challenge with no effective treatments. This study introduces a novel hydrogen‐gene therapy strategy, combining focused ultrasound and siRNA delivery via hydrogen emitters, to repair neuroinflammation in a precise and controlled manner.
Ruonan Zhan   +11 more
wiley   +1 more source

A strain of <i>Streptococcus mitis</i> inhibits biofilm formation of caries pathogens via abundant hydrogen peroxide production. [PDF]

open access: yesAppl Environ Microbiol
Williams I   +6 more
europepmc   +1 more source

TRIM25‐Mediated INSIG1 Ubiquitination Promotes MASH Progression Through Reprogramming Lipid Metabolism

open access: yesAdvanced Science, EarlyView.
TRIM25‐mediated ubiquitination of INSIG1 serves as a key driver of lipid metabolism dysregulation in MASH progression. It identifies a novel small‐molecule inhibitor, C27H26N2O4S, which effectively inhibits TRIM25 activity, reducing lipid accumulation and inflammation.
Hao Zhang   +8 more
wiley   +1 more source

Sub-organellar mitochondrial hydrogen peroxide observed using a SNAP tag targeted coumarin-based fluorescent reporter. [PDF]

open access: yesRedox Biol
Eaglesfield R   +7 more
europepmc   +1 more source

Photopatternable PEDOT:PSS Hydrogels for High‐Resolution Photolithography

open access: yesAdvanced Science, EarlyView.
A photosensitive biphasic conducting polymer hydrogel (PB‐CH) is rationally designed with PEDOT:PSS as the conductive phase and a light‐sensitive matrix as the mechanical phase. Such a PB‐CH offers a unique combination of excellent conductivity (≈30 S cm⁻¹), robust mechanical performance (with stretchability up to 50%), and high photopatternability ...
Wen Wang   +7 more
wiley   +1 more source

Establishment of a mouse model of ovarian oxidative stress induced by hydrogen peroxide. [PDF]

open access: yesFront Vet Sci
Liang H   +10 more
europepmc   +1 more source

Antagonist Targeting the Species‐Specific Fatty Acid Dehydrogenase/Isomerase FabX for Anti‐H. pylori Infection

open access: yesAdvanced Science, EarlyView.
This study demonstrates that the atypical dehydrogenase/isomerase FabX in Type‐II fatty acid biosynthesis pathway is essential for H. pylori infection by retaining unsaturated fatty acid synthesis and producing superoxide (ROS). A small molecule FBX‐1991 that specifically targets FabX to inhibit H.
Lin Zhang   +9 more
wiley   +1 more source

Hydrogen peroxide damage to rat liver sinusoidal endothelial cells is prevented by n-acetyl-cysteine but not GSH. [PDF]

open access: yesHepatol Commun
Kruse LD   +7 more
europepmc   +1 more source

Vessel‐On‐A‐Chip Coupled Proteomics Reveal Pressure‐Overload‐Induced Vascular Remodeling

open access: yesAdvanced Science, EarlyView.
A vessel‐on‐a‐chip system is developed to replicate both physiological and pathological vessel cyclic stretches. Proteomic analysis reveals pressure‐overload‐induced vascular remodeling, including cellular response to mechanical cues, cellular oxidative stresses, ER stress, and ceramide biosynthesis activation in the vessel‐on‐a‐chip system, well ...
Yanjun Liu   +11 more
wiley   +1 more source

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