Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Hydrogen production econometric studies [PDF]
The current assessments of fossil fuel resources in the United States were examined, and predictions of the maximum and minimum lifetimes of recoverable resources according to these assessments are presented.
Bannerot, R. B., Howell, J. R.
core +1 more source
Effects of several inocula on the biochemical hydrogen potential of sludge-vinasse co-digestion [PDF]
, 2019 The influence of the inoculum on the Biochemical Hydrogen Potential test (BHP) was investigated. Thermophilic BHP from sludge-vinasses co-digestion (50:50) was studied employing three types of inocula: Acidogenic Inoculum, Sludge Inoculum and Thermal ...
Akhlaghi +43 more
core +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
An economic analysis of the production of hydrogen from wind-generated electricity for use in transport applications [PDF]
Wind-generated electricity is often considered a particularly promising option for producing hydrogen from renewable energy sources. However, the economic performances of such systems generally remain unclear because of unspecified or favorable ...
Alain Le Duigou +3 more
core
Next Steps for Hydrogen - physics, technology and the future [PDF]
, 2016 Hydrogen has been proposed as a future energy carrier for more than 40 years. In recent decades, impetus has been given by the need to reduce global greenhouse gas emissions from vehicles.
Glowacki, Bartek +2 more
core
Phenol degradation using 20, 300 and 520 kHz ultrasonic reactors with hydrogen peroxide, ozone and zero valent metals [PDF]
, 2009 The extent of phenol degradation by the advanced oxidation process in the presence of zero valent iron (ZVI) and zero valent copper (ZVC) was studied using 20, 300 and 520 kHz ultrasonic (US) reactors.
Bremner, David H. +3 more
core +3 more sources
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
A novel hybrid architecture for agriculture and land use in an integrated modeling framework : MATISSE (Methods and Tools for Integrated Sustainability Assesment) [PDF]
, 2008 As part of a cluster workshop on sustainability of hydrogen transport technologies held in Frankfurt on 21st February 2006, MATISSE researchers conducted break-out discussion groups with, and distributed self-completion questionnaires to, stakeholders in
Cassen, Christophe +4 more
core
Hydrogen production by electrolysis of a phosphate solution on a stainless steel cathode [PDF]
, 2010 The catalytic properties of phosphate species, already shown on the reduction reaction in anaerobic corrosion of steels, are exploited here for hydrogen production.
Basséguy, Régine +3 more
core +2 more sources