Results 61 to 70 of about 566,619 (267)

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Solar-driven Redox Hydrogen Production [PDF]

E3S Web of Conferences
The climate crisis requires urgent actions to reduce the global temperature. Renewable energy and electro-chemicals are expected to play a growing role in sustainable power solutions moving forward.
Deng Yimin, Liu Helei, Luo Hui, Bai Liju, Yang Miao, Baeyens Jan   +5 more
doaj   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Improved adsorptive separation of palladium ions from wastewater using metal-organic framework modified with poly(m-phenylenediamine)

Chemical Physics Impact
A novel metal-organic framework decorated with poly(m-phenylenediamine) (PmPD/MIL-101(Cr) composite for adsorption of Pd ion from wastewater was synthesised.
Khaleke V. Ramollo, Gift Mello, Kwena D. Modibane, Nomso C. Hintsho-Mbita, Thabiso C. Maponya   +4 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Hot deformation constitutive modeling of 6111 aluminum alloy linking Z-parameter to the associated microstructural evolution and precipitation strengthening

Journal of Materials Research and Technology
This work investigates the hot deformation behavior and microstructure evolution of 6111 aluminum alloy (core layer in 4343/3003/6111/3003 brazed sheets) via thermal compression (300–500 °C, 0.01–10 s−1). A strain-compensated Arrhenius constitutive model
Minglong Kang, Yunlai Deng, Fei Du, Shuhui Liu, Binhu Wang, Ming-Chun Zhao   +5 more
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Hydrogen as an Energy Carrier—An Overview over Technology, Status, and Challenges in Germany

J
Hydrogen is set to become an important energy carrier in Germany in the next decades in the country’s quest to reach the target of climate neutrality by 2045.
Caroline Willich
doaj   +1 more source