Results 41 to 50 of about 1,390,857 (294)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Coordinated Optimization of Intelligent Soft Open Points and Multiple Types of Shared Energy Storage in Distribution Networks Considering Flexibility Deficiency Risk

发电技术
ObjectivesTo address the operational security issues in the new-type distribution network caused by the high-penetration integration of renewable energy, this paper proposes a coordinated optimization method for intelligent soft open points and multiple ...
WANG Jie, XU Lijun, LI Xiaozhu, FAN Xiaochao, GULIZHATI∙Hailati, WANG Weiqing   +5 more
doaj   +1 more source

Antioxidant and Chemosensitizing Effects of Flavonoids with Hydroxy and/or Methoxy Groups and Structure-Activity Relationship

Journal of Pharmacy & Pharmaceutical Sciences, 2007
Purpose. Flavonoids have been used as antioxidant, chemopreventive and chemosensitizing agents. In this study, eleven flavonoids containing a variety of hydroxy (OH) and/or methoxy (OMe) groups were evaluated for their antioxidant, cytotoxic and ...
Ju-Mi Jeong, Cheol-Hee Choi, Su-Kyeong Kang, In-Hwa Lee, Ji-Yoon Lee, Hyuk Jung   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Unlocking the potential of sugarcane leaf waste for sustainable methane production: Insights from microbial pre-hydrolysis and reactor optimization

Heliyon
Sugarcane leaf waste, a byproduct of the growing global sugar industry, challenges agricultural waste management. This study explores its potential for methane production via anaerobic digestion. A microbial pre-hydrolysis, using lignocellulose-degrading
Napapat Sitthikitpanya, Chaweewan Ponuansri, Umarin Jomnonkhaow, Nantharat Wongfaed, Alissara Reungsang   +4 more
doaj   +1 more source

Development Route of Hydrogen Production by Water Electrolysis, Hydrogen Storage and Hydrogen Supply in Power System

发电技术, 2023
Hydrogen energy has broad development prospects as a clean, carbon-free, flexible and efficient secondary energy and industrial raw material. Although the technologies of hydrogen production by water electrolysis, hydrogen storage and hydrogen supply ...
ZHANG Chunyan, DOU Zhenlan, WANG Jun, ZHU Liangliang, SUN Xiaotong, LI Gendi   +5 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Hydrogen peroxide generation by DC and pulsed underwater discharge in air bubbles [PDF]

, 2012
The generation of H(2)O(2) in underwater discharge in air bubbles is studied with consideration of the influence of electrodes polarity, input power, solution conductivity and the inter-electrode distance.
Xiong, Ranhua, Nikiforov, Anton, Vanraes, Patrick, Leys, Christophe   +3 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Hydrogen Production by Water Electrolysis Via Photovoltaic Panel

Journal of Engineering, 2016
Hydrogen fuel is a good alternative to fossil fuels. It can be produced using a clean energy without contaminated emissions. This work is concerned with experimental study on hydrogen production via solar energy.
Hydrogen Production by Water Electrolysis Via Photovoltaic Panel, Sameer Mohammmed Salman, Zahraa Hashim Kareem   +2 more
doaj