Results 61 to 70 of about 1,318,053 (287)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Morphological changes and kinetic assessment of Cu2O powder reduction by non-thermal hydrogen plasma

Journal of Materials Research and Technology, 2021
Non-thermal hydrogen plasma is a novel reducing medium that can yield H2 derived species capable of improving the reduction efficiency of metallic oxides when compared to a conventional reduction by hydrogen gas.
S.V. Ramos, P. Cisquini, R.C. Nascimento Jr., A.R. Franco Jr., E.A. Vieira   +4 more
doaj   +1 more source

Study of the influence of phosphoric acid in steel anaerobic corrosion via the hydrogen evolution reaction. [PDF]

, 2007
Although it is well known that the phosphate species are quiet electrochemically inert when considering their calculated redox potential, few studies since the end of 80’s reported electrochemical phenomenon observed in the reduction domain which were ...
Basséguy, Régine, Bergel, Alain, De Silva Munoz, Leonardo   +2 more
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Recycling of Valuable Metals from the Priority Lithium Extraction Residue Obtained through Hydrogen Reduction of Spent Lithium Batteries

Batteries
The selective separation of lithium from spent ternary positive materials is achieved through hydrogen reduction followed by water leaching. Almost 98% of the Li is transformed into soluble LiOH⋅H2O, while the Ni, Co and Mn species are all transformed ...
Yong Guo, Fupeng Liu, Feixiong Chen, Zaoming Chen, Hong Zeng, Tao Zhang, Changquan Shen   +6 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

A MOLECULAR DYNAMICS STUDY OF THE INFLUENCE OF CHEMICAL REDUCTION ON THE STRUCTURE OF AMORPHOUSE GERMANIA

TASK Quarterly, 2002
The contribution is dedicated to the molecular dynamics (MD) study of the structure of reduced germania glass of composition 1Ge 1GeO2. The work is inspired by a recent report on the formation of Ge clusters in hydrogen reduced germanate glasses ...
AGNIESZKA WITKOWSKA, LEON MURAWSKI, GRZEGORZ BERGMAŃSKI   +2 more
doaj  

Synthesis of Polycrystalline Bi-Doped Snse by Mechanical Alloying and Hydrogen Reduction [PDF]

Archives of Metallurgy and Materials
In this study, Bi-doped SnSe was fabricated through the high energy ball milling and the hydrogen reduction of Bi2O3, and its thermoelectric properties were analyzed.
Jin Kwang Jang, Jaeyun Moon, Jongmin Byun   +2 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source