Results 41 to 50 of about 1,942,364 (283)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

A Fault Diagnosis and Reconfiguration Strategy for Self-Validating Hydrogen Sensor Array Based on MWPCA and ELM

IEEE Access, 2019
The flammable and explosive property of hydrogen is the main danger in its safe use, storage and transportation. In this paper, a novel hydrogen monitoring system is designed based on the principle of semiconductor, catalytic combustion and heat ...
Kai Song, Peng Xu, Yinsheng Chen, Tinghao Zhang, Guo Wei, Qi Wang   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Palladium nanofiber networks hydrogen sensor and hydrogen-actuated switches

, 2019
This paper presents a novel fabrication technique for hydrogen gas sensor based on polymer nanofiber and pure palladium metal. The polymer nanofiber was produced from 7 wt% poly vinyl alcohol (PVA) solution through electrospinning system.
Ataur Rahman, M, Dao, DV, Hawkett, B, Wang, B, Huynh, V, Zhu, Y, Sriram, S   +6 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Recent Advances and Challenges of Nanomaterials-Based Hydrogen Sensors

Micromachines, 2021
Safety is a crucial issue in hydrogen energy applications due to the unique properties of hydrogen. Accordingly, a suitable hydrogen sensor for leakage detection must have at least high sensitivity and selectivity, rapid response/recovery, low power ...
Bei Wang, Ling Sun, Martin Schneider-Ramelow, Klaus-Dieter Lang, Ha-Duong Ngo   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

An advanced performance preservation method for surface acoustic wave hydrogen sensors based on graphene sensitive layers

Alexandria Engineering Journal
High-performance hydrogen sensors are essential for efficiently utilizing hydrogen energy. We developed a high-performance surface acoustic wave sensor hydrogen sensor by integrating the advantages of surface acoustic wave technology (high sensitivity ...
Xuan Zhao, Shu Zhu, Xiaoqi Wu
doaj   +1 more source

Fabrication of Nanoporous Platinum Films with Dealloying Method for Hydrogen Sensor Application

Engineering Proceedings, 2022
In this research, a nanoporous platinum film is synthesized using the dealloying method. Platinum–copper (Pt–Cu) alloy films with a thickness of approximately 50 nm are prepared on glass using the magnetron-co-sputtering technique.
Melike Sener, Ali Altuntepe, Recep Zan, Necmettin Kilinc   +3 more
doaj   +1 more source