Results 51 to 60 of about 1,942,364 (283)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Enabling the injection of hydrogen in high-pressure gas grids: Investigation of the impact on materials and equipment [PDF]

, 2023
Publisher Copyright: © 2023 Hydrogen Energy Publications LLCGreen hydrogen is a renewable gas that can help to reach the goal of decarbonizing the energy sector.
Madina, Virginia, Alberto Cerezo, Ekain Fernandez, Vanesa Gil, Cerezo, Alberto, Ma Dolores Storch de Gracia, Storch de Gracia, Ma Dolores, Virginia Madina, Fernandez, Ekain, Jorge Aragón, Aragón, Jorge, Sánchez-Laínez, Javier, Gil, Vanesa, Javier Sánchez-Laínez   +13 more
core   +1 more source

An irreversible hydrogenochromic sensor applicable to corrosion environments with high sensitivity and high spatial resolution

npj Materials Degradation
To visualize hydrogen entry and diffusion into metals under high humidity corrosion conditions, an irreversible hydrogenochromic sensor was fabricated using polyaniline and resin layers.
Zhenting Wang, Saya Ajito, Yongxin Wang, Motomichi Koyama, Eiji Akiyama, Hiroshi Kakinuma   +5 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Chemical Hydride Slurry for Hydrogen Production and Storage [PDF]

, 2008
The purpose of this project was to investigate and evaluate the attractiveness of using a magnesium chemical hydride slurry as a hydrogen storage, delivery, and production medium for automobiles.
McClaine, Andrew W.
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Palladium based membranes and membrane reactors for hydrogen production and purification:An overview of research activities at Tecnalia and TU/e [PDF]

, 2016
In this paper, the main achievements of several European research projects on Pd based membranes and Pd membrane reactors for hydrogen production are reported.
E. Fernandez, Spallina, V., de Nooijer, N.C.A., A. Arratibel, F. Gallucci, D.A. Pacheco Tanaka, Melendez, J., Gallucci, F., Pacheco Tanaka, D. A., M. van Sint Annaland, Zuniga Palacio, Jon, Zuñiga, J., Fernandez, Ekain, Arratibel, A., Helmi Siasi Farimani, A., V. Spallina, Fernandez, E., Helmi, A., J. Melendez, Medrano Jimenez, J.A., de Nooijer, N. C.A., Coenen, K.T., Pacheco Tanaka, D.A., Melendez Rey, J., Viviente, J. L., J.L. Viviente, Medrano, J. A., van Sint Annaland, M., J. Zuñiga, Gallucci, F.; id_orcid, Coenen, K., K. Coenen, Viviente, J.L., A. Helmi, J.A. Medrano, Spallina, V.; id_orcid, Arratibel Plazaola, A., N.C.A. de Nooijer   +37 more
core   +4 more sources