Results 11 to 20 of about 91,703 (108)

Ribonucleotide reductase in dividing cells: Purification and inhibition studies with 4-hydroxynonenal [PDF]

, 1992
This thesis was submitted for the degree of Doctor of Philosophy and was awarded by Brunel University.1). The effect of temperature, P450 inhibitors (pyrazole and imidazole), sulphydryl reagents (iodoacetamide and N-ethyl maleimide) and glutathione on ...
Li, Li
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Immunocytochemical localization of APS reductase and bisulfite reductase in three Desulfovibrio species [PDF]

, 1988
The localization of APS reductase and bisulfite reductase in Desulfovibrio gigas, D. vulgaris Hildenborough and D. thermophilus was studied by immunoelectron microscopy.
Moura, J.J.G., Kremer, D.R., LeGall, J., Lampreia, J.,, Veenhuis, M.,, KREMER, DR, LAMPREIA, J, VEENHUIS, M, HANSEN, TA, MOURA, JJG, Hansen, T.A., Peck Jr., H.D.,, LeGall, J.,, Kremer, D.R.,, Fauque, G., Lampreia, J., FAUQUE, G, Veenhuis, M., Moura, J.J.G.,, Peck Jr., H.D., Hansen, T.A.,, LEGALL, J, PECK, HD, Fauque, G.,   +23 more
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Structure based design and synthesis of antiparasitic pyrrolopyrimidines targeting pteridine reductase 1 [PDF]

, 2014
The treatment of Human African Trypanosomiasis remains a major unmet health need in sub-Saharan Africa. Approaches involving new molecular targets are important and pteridine reductase 1 (PTR1), an enzyme that reduces dihydrobiopterin in Trypanosoma spp.
Kirsten Stewart, Michael P. Barrett, Pui Ee Wong, William N. Hunter, Barrack, Keri L., Hunter, William N., Huggan, Judith, Colin L. Gibson, Judith K. Huggan, Barrett, Michael P., Federica Giordani, Suckling, Colin J., Colin J. Suckling, Khalaf, Abedawn I., Huggan, Judith K., Wong, Pui Ee, Khalaf, Abedawn I, Barrack, Keri L, Stewart, Kirsten, Keri L. Barrack, Suckling, Colin J, Hunter, Wililam N., Gibson, Colin L., Giordani, Federica, Gibson, Colin L, Abedawn I. Khalaf, Hunter, William N   +26 more
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FAD binding, cobinamide binding and active site communication in the corrin reductase (CobR) [PDF]

, 2014
Adenosylcobalamin, the coenzyme form of vitamin B12, is one Nature's most complex coenzyme whose de novo biogenesis proceeds along either an anaerobic or aerobic metabolic pathway. The aerobic synthesis involves reduction of the centrally chelated cobalt
Pickersgill, Richard W., Pickersgill, Richard W, Howard, Mark J., Mark J. Howard, Alan Scott, Christopher M. Johnson, Stephen E. J. Rigby, Rigby, Stephen E J, Lawrence, Andrew D., Taylor, Samantha L., Rigby, Stephen E.J., Andrew D. Lawrence, Rowe, Michelle L., Scott, Alan, Samantha L. Taylor, Johnson, Christopher M, Michelle L. Rowe, Taylor, Samantha L, Rigby, Stephen E. J., Geeves, Michael A., Richard W. Pickersgill, Warren, Martin J., Johnson, Christopher M., Michael A. Geeves, Martin J. Warren   +24 more
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Mutations in SRD5B1 (AKR1D1), the gene encoding Delta(4)-3-oxosteroid 5 beta-reductase, in hepatitis and liver failure in infancy [PDF]

, 2003
Background: A substantial group of patients with cholestatic liver disease in infancy excrete, as the major urinary bile acids, the glycine and taurine conjugates of 7alpha-hydroxy-3-oxo-4-cholenoic acid and 7alpha, 12alpha-dihydroxy-3- oxo-4-cholenoic ...
Duran, M., Scambler, PJ, Custard, E. J., Bouquet, J, Lemonde, H. A., Clayton, P. T., Duran, M, Overmars, H, Bouquet, J., Scambler, P.J., Lemonde, H., Clayton, P.T., Custard, EJ, Scambler, P. J., Clayton, PT, Lemonde, HA, Custard, E.J., Overmars, H.   +17 more
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Investigating the biosynthesis of heam d1 in pseudomonas aeruginosa: a cofactor for dissimilatory nitrite reductase. [PDF]

, 2010
PhDHaem d1 is a modified tetrapyrrole unique to the periplasmic enzyme nitrite reductase where it acts in catalysing the reduction of nitrite (NO2 -) to nitric oxide (NO), as part of denitrification.
Parmar-Bhundia, Vina
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Dynamics of immobilized and native Escherichia coli dihydrofolate reductase by quasielastic neutron scattering [PDF]

, 2006
The internal dynamics of native and immobilized Escherichia coli dihydrofolate reductase (DHFR) have been examined using incoherent quasielastic neutron scattering.
Smith, J.C., Ollivier, Jacques, Kurkal, V., Monk, C., Oettl, M., Finney, J.L., Tehei, Moeava, Monk, Colin R., Kurkal, Vandana, Smith, Jeremy C., Tehei, M., Finney, John L., Ollivier, J., Oettl, Martin, Daniel, R.M., Daniel, Roy M.   +15 more
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Hydrogen-Bonded Networks Along and Bifurcation of the E-Pathway in Quinol:Fumarate Reductase [PDF]

, 2012
peer reviewedThe E-pathway of transmembrane proton transfer has been demonstrated previously to be essential for catalysis by the diheme-containing quinol:fumarate reductase (QFR) of Wolinella succinogenes.
Juhnke, Hanno Dominik, Juhnke, H., Simon, Joerg, Maentele, Werner, Lancaster, C. Roy D., Mäntele, W., Haas, A., Helms, Volkhard, Mäntele, Werner, Simon, J., Juhnke, Hanno D., Gu, W., Herzog, E., Herzog, Elena, Lancaster, C., Haas, Alexander H., GU, Wei, Simon, Jörg, Volkhard, H.   +18 more
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Effects of myosin heavy chain (MHC) plasticity induced by HMGCoA-reductase inhibition on skeletal muscle functions. [PDF]

, 2011
The rate-limiting step of cholesterol biosynthetic pathway is catalyzed by 3-hydroxy-3-methylglutaryl coenzyme reductase (HGMR), whose inhibitors, the statins, widely used in clinical practice to treat hypercholesterolemia, often cause myopathy, and ...
Moreno, Sandra, Swiezewska, Ewa, Linari, Marco, Fanelli, Francesca, V. Trezza, Segatto, Marco, L. Melli, Marco Segatto, L. p. Pucillo, Patrizia Campolongo, Pallottini, Valentina, Laura Trapani, Leopoldo Paolo Pucillo, Viviana Trezza, S. Moreno, F. Fanelli, A. Jozwiak, M. Segatto, V. Pallottini, Campolongo, Patrizia, Melli, Luca, Sandra Moreno, Francesca Fanelli, Marco Linari, Trezza, Viviana, E. Swiezewska, L. Trapani, Trapani, Laura, Valentina Pallottini, Adam Jozwiak, Luca Melli, Ewa Swiezewska, Jóźwiak, Adam, M. Linari, Pucillo, Leopoldo Paolo   +34 more
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The methylenetetrahydrofolate reductase C677T genotype and the risk of obesity in three large population-based cohorts. [PDF]

, 2008
OBJECTIVE: Epidemiological studies have shown that low folate levels are associated with a high body mass index (BMI). These findings have potentially important health implications and warrant further investigation to determine whether a causal ...
Nordestgaard, B, Tybjaerg-Hansen, A, Lewis, Sarah J, Zacho, J., Lawlor, Debbie A, Ebrahim, S, Smith, G.D., Lewis, S.J., Ebrahim, S., Davey Smith, G, Ebrahim, Shah, Tybjaerg-Hansen, A., Leary, SD, Leary, Sam, Ness, Andy, Lawlor, D, Smith, George Davey, Ness, A., Lewis, SJ, Zacho, J, Zacho, Jeppe, Leary, S., Nordestgaard, Børge G, Nordestgaard, B.G., Tybjaerg-Hansen, Anne, Ness, A, Lawlor, D.A.   +26 more
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