Results 21 to 30 of about 91,703 (108)

Silver inhibition on recombinant flavin reductase from Citrobacter freundii A1 [PDF]

, 2012
In this study, the flavin reductase (Fre) of Citrobatter freundii A1 was expressed in E. coli DH5a host with 1 mM IPTG induction. This recombinant protein was fused to 6xHis-tag, thus promising easier IMAC purification of the expressed enzyme.
Mamat, Nor Sasha Izana
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Molecular monitoring of the Leu-164 mutation of dihydrofolate reductase in a highly sulfadoxine/pyrimethamine-resistant area in Africa. [PDF]

, 2003
The selection of point mutation at codon 164 (from isoleucine to leucine) of the dihydrofolate reductase (DHFR) enzyme in Plasmodium falciparum is associated with high sulfadoxine /pyrimethamine (SP) resistance.
Watkins, W, Kimani, S, Kimani Serah, Kokwaro, Gilbert, Nzila, A, Mutabingwa, T, Kevin Marsh, Theonest Mutabingwa, Serah Kimani, Mutabingwa, Theonest, Gilbert Kokwaro, Nzila Alexis, Ochong, Edwin, Nzila, Alexis, Edwin Ochong, Kokwaro Gilbert, Kimani, Serah, Marsh Kevin, Marsh, K, Ochong Edwin, Alexis Nzila, Watkins, William, William Watkins, Kokwaro, G, Watkins William, Marsh, Kevin, Mutabingwa Theonest, Ochong, E   +27 more
core   +1 more source

Mechanistic Insights into the Ene-Reductase-Catalyzed Promiscuous Reduction of Oximes to Amines

, 2023
The biocatalytic reduction of the oxime moiety to the corresponding amine group has only recently been found to be a promiscuous activity of ene-reductases transforming α-oximo β-keto esters.
Wolfgang Kroutil (1279629), Silvia M. Glueck, Bastian Daniel, Willem B. Breukelaar (14572922), Amit Singh, Wolfgang Kroutil, Nakia Polidori (14572925), Karl Gruber, Willem B. Breukelaar, Silvia M. Glueck (1285218), Bastian Daniel (2825576), Nakia Polidori, Amit Singh (130923), Karl Gruber (141169)   +13 more
core   +1 more source

Analysis of nitrate reductase mRNA expression and nitrate reductase activity in response to nitrogen supply

, 2014
Nitrate is one of the major sources of nitrogen for the growth of plants. It is taken up by plant roots and transported to the leaves where it is reduced to nitrite in the.
Eshghi, Homeira, Balotf, Sadegh, Kavoosi, Gholamreza, Hasani, Hasan   +3 more
core   +1 more source

Novel Lead Generation through Hypothetical Pharmacophore Three-Dimensional Database Searching:  Discovery of Isoflavonoids as Nonsteroidal Inhibitors of Rat 5α-Reductase

, 2016
A hypothetical pharmacophore of 5α-reductase inhibitors was generated and served as a template in virtual screening. When the pharmacophore was used, eight isoflavone derivatives were characterized as novel potential nonsteroidal inhibitors of rat 5α ...
Chih-Shiang Chang (2361178), Grace Shiahuy Chen (2374888), Wai Ming Kan (3013248), Chih-Long Chang (436219), K. C. Wang (3013245), Ji-Wang Chern (1912126)   +5 more
core   +1 more source

Ferredoxin-sulfite reductase and ferredoxin-nitrite reductase activities in leaves of Pisum sativum: Changes during ontogeny and in vitro regulation by sulfide [PDF]

, 1985
Since ferredoxin‐dependent sulfite reductase (EC 1.8.7.1) and nitrite reductase (EC 1.7.7.1) can both catalyze the reduction of SO2‐3 and NO−2, physiological and biochemical evidence is needed for properly classifying the two enzyme activities. They were
Brunold, Christian, Arb, Christoph
core   +1 more source

Spectroscopic and theoretical approaches for studying radical reactions in class I ribonucleotide reductase [PDF]

, 2005
Ribonucleotide reductases (RNRs) catalyze the production of deoxyribonucleotides, which are essential for DNA synthesis and repair in all organisms.
Lendzian, F., Bennati, Marina, Schmittle, M., Schmittel, Michael, Zipse, H., Lendzian, Friedhelm, Bennati, M., Zipse, Hendrik   +7 more
core   +1 more source

The Plant Short-Chain Dehydrogenase (SDR) superfamily:genome-wide inventory and diversification patterns [PDF]

, 2012
Background Short-chain dehydrogenases/reductases (SDRs) form one of the largest and oldest NAD(P)(H) dependent oxidoreductase families. Despite a conserved 'Rossmann-fold' structure, members of the SDR superfamily exhibit low sequence similarities, which
Moummou, Hanane, Persson, B, van der Rest, Benoit,, Libert Brice Tonfack, Tonfack, LB, Tonfack, Libert Brice, Kallberg, Yvonne, Persson, Bengt, Bengt Persson, Kallberg, Y,, Benoît van der Rest, Moummou, Hanane,, Yvonne Kallberg, Brice Tonfack, Libert, Persson, Bengt,, Hanane Moummou, Van der Rest, Benoît, Kallberg, Yvonne,, Brice Tonfack, Libert,, van, der Rest B, Moummou, H, Moummou Hanane, Tonfack Libert Brice, Persson Bengt, Kallberg Yvonne, van der Rest Benoît   +25 more
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Examination of the brassica napus β-Keto-Acyl carrier protein reductase promoter for regulatory Cis-acting elements [PDF]

, 2002
Major interest has focused on the identification of regulatory factors involved in lipid biosynthesis. This study examined the B.napus β-Keto-ACP reductase 5' sequence for potential regulatory cis-acting elements.
Young, Clare Elisabeth
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Pleiotropic effects of the HMG-CoA reductase inhibitors

, 2011
Christos G Mihos, Orlando SantanaColumbia University Division of Cardiology, Mount Sinai Heart Institute, Miami Beach, FL, USAAbstract: The HMG-CoA reductase inhibitors (statins) are used extensively in the treatment of hyperlipidemia.
Santana O, Mihos CG, Orlando Santana, C Mihos   +3 more
core   +1 more source