Results 111 to 120 of about 297,801 (378)

Nanoparticle‐Mediated CXCL12–CXCR4 Inhibition Reprograms Macrophages and Suppresses Gastric Carcinoma

open access: yesAdvanced Science, EarlyView.
Molecular mechanism study of self‐assembled M2pep‐Cs NPs/Plerixafor nanoparticles in targeting MΦ reprogramming by regulating the CXCL12–CXCR4 signaling pathway to enhance immune recognition and clearance of GC (Created by BioRender). Abstract Gastric carcinoma (GC) remains a major global health challenge, requiring novel therapeutic approaches.
Qianqian Cao   +9 more
wiley   +1 more source

Gut Metabolite Indole‐3‐Propionic Acid Regulates Macrophage Autophagy Through PPT1 Inhibiting Aging‐Related Myocardial Fibrosis

open access: yesAdvanced Science, EarlyView.
IPA is an intestinal tryptophan metabolite whose effects decline with decreased heart function. Supplementing IPA can alleviate the aging‐related myocardial fibrosis through PPT1. PPT1 is a key protein localized to lysosomes, and IPA can restore macrophage autophagy function by regulating PPT1 expresssions, thereby reducing aging‐related myocardial ...
Jing Lu   +16 more
wiley   +1 more source

Drosophila melanogaster mutant tan [PDF]

open access: yes, 2009
Drosophila melanogaster gene tan was originally discovered in the early 20th century as a mutant strain lacking the dark pi gment pattern of wild-type (wt) f lies and, therefore, showing a light yellowish brown color (McEwen, 1918 ...
Badaracco, Alejandra   +2 more
core  

The Spermatophore in Glossina morsitans morsitans: Insights into Male Contributions to Reproduction. [PDF]

open access: yes, 2016
Male Seminal Fluid Proteins (SFPs) transferred during copulation modulate female reproductive physiology and behavior, impacting sperm storage/use, ovulation, oviposition, and remating receptivity.
Abd-Alla, Adly MM   +8 more
core   +2 more sources

Enzymatic diversity in the haloactinomycetes isolated from rhizosphere of the plants in saline soils at the periphery of Dasht-e-Kavir desert

open access: yesیافته‌های نوین در علوم زیستی, 2022
Saline rhizospheric areas are untouched environments for isolating actinomycetes with the potential of valuable salt tolerant enzyme production. In this study, we isolated and evaluated a total number of of 26 actinomycete strains from plant rhizosphere ...
Ensieh Salehghamari
doaj  

Evolution, substrate specificity and subfamily classification of glycoside hydrolase family 5 (GH5)

open access: yesBMC Evolutionary Biology, 2012
BackgroundThe large Glycoside Hydrolase family 5 (GH5) groups together a wide range of enzymes acting on β-linked oligo- and polysaccharides, and glycoconjugates from a large spectrum of organisms. The long and complex evolution of this family of enzymes
H. Aspeborg   +4 more
semanticscholar   +1 more source

The SlDOF9‐SlSWEET17 Module: a Switch for Controlling Sugar Distribution Between Nematode Induced Galls and Roots in Tomato

open access: yesAdvanced Science, EarlyView.
Root‐knot nematode (RKN) disease seriously affects the yield and quality of vegetable crops. SlDOF9‐SlSWEET17 model helps plants resist RKN infection during early stage by switching off the sugar transport capacity of other SlSWEET proteins that are hijacked by RKNs.
Xiaoyun Wang   +14 more
wiley   +1 more source

Expanding the Toolkit for the Serine Hydrolases

open access: yesChemistry & Biology, 2015
In this issue of Chemistry & Biology, Cognetta et al. (2015) describe new pharmacological tools, including N-hydroxyhydantoin-containing carbamate inhibitors and an activity-based probe, for palmitoyl protein thioesterase 1 and alpha, beta-hydrolase domain-4 that expand the toolkit for the serine hydrolases.
Ran Wang, Matthew K. Ross
openaire   +3 more sources

Trimerization of 1,2‐Diaminocyclohexane Catalyzed by a Metal–Organic Cage Tandem Catalyst with Dual Biomimetic Active Sites

open access: yesAdvanced Science, EarlyView.
Dual biomimetic active sites, i.e., mononuclear {ZnII(L)(H2O)} and dinuclear {L2ZnII(CHO2)(OH)ZnIIL2}, have been successfully intergrated into a metal–organic cage, Zn20‐MOC. These two different active sites in Zn20‐MOC catalyze different steps of cascade trimerization of 1,2‐diaminocyclohexane. The mononuclear {ZnII(L)(H2O)} site catalyzes the initial
Xiao‐Jun Chai   +10 more
wiley   +1 more source

Potential of Lactic Acid Bacteria Isolated From Dangke and Indonesian Beef as Hypocholesterolaemic Agent [PDF]

open access: yes, 2017
Lactobacillus fermentum strains were successfully isolated from dangke which was a fresh cheese-like product originating from Enrekang, South Sulawesi Province, Indonesia.
Arief, I. I. (I)   +3 more
core  

Home - About - Disclaimer - Privacy