Results 111 to 120 of about 130,442 (303)

Phototherapy via Modulation of β‐Amyloid in Combating Alzheimer's Disease

Aggregate, EarlyView.
This review introduces the light‐regulated Aβ aggregation, highlighting four applications: photodynamic therapy (PDT), photothermal therapy (PTT), photopharmacology, and photobiomodulation (PBM) systems. It also summarizes the current issues and proposes the prospects of photo‐induced modulation of Aβ aggregation and clearance as a therapeutic strategy
Yunhua Zhang, Chengyuan Qian, Yuncong Chen, Weijiang He, Zijian Guo   +4 more
wiley   +1 more source

Vitamin B12 Levels Association with Functional and Structural Biomarkers of Central Nervous System Injury in Older Adults

Annals of Neurology, EarlyView.
At low levels of B12, specifically when bound to transcobalamin for cellular uptake, evidence of slower conductivity in the brain could point toward impaired myelin. At high levels of B12, specifically when bound to the biologically inert transport protein haptocorrin, biomarkers of neurodegeneration appear in the serum, indicating neuroaxonal injury ...
Alexandra Beaudry‐Richard, Ahmed Abdelhak, Rowan Saloner, Simone Sacco, Shivany C. Montes, Frederike C. Oertel, Christian Cordano, Nour Jabassini, Kirtana Ananth, Apraham Gomez, Azeen Keihani, Makenna Chapman, Sree Javvadi, Shikha Saha, Adam Staffaroni, Christopher Songster, Martin Warren, John W. Boscardin, Joel Kramer, Bruce Miller, Joshua W. Miller, Ralph Green, Ari J. Green   +22 more
wiley   +1 more source

SARS coronavirus protein 7a interacts with human Ap₄A-hydrolase

Virology Journal, 2010
The SARS coronavirus (SARS-CoV) open reading frame 7a (ORF 7a) encodes a 122 amino acid accessory protein. It has no significant sequence homology with any other known proteins.
Zakhartchouk Alexander, Moshynskyy Igor, Vasilenko Natalia   +2 more
doaj   +1 more source

Acid hydrolases of the rat uterus in relation to pregnancy, post-partum involution and collagen breakdown [PDF]

, 1965
JF WOESSNER
openalex   +1 more source

Characterization and engineering of plastic-degrading polyesterases jmPE13 and jmPE14 from Pseudomonas bacterium

Frontiers in Bioengineering and Biotechnology
Polyester plastics are widely used in daily life, but also cause a large amount of waste. Degradation by microbial enzymes is the most promising way for the biobased upcycling of the wastes. However, there is still a shortage of high-performance enzymes,
Xiaoli Zhou, Xianmin Zhou, Zhiqiang Xu, Mingxia Zhang, Honghui Zhu   +4 more
doaj   +1 more source

Konvergenter Aufbau Homo‐ und Heterotypischer Ubiquitinketten aus funktionaliserten, exprimierten Monomeren mittels Thiol‐En‐Chemie

Angewandte Chemie, EarlyView.
Die Erzeugung funktionalisierter Ubiquitinbausteine mittels Expression in E. coli bietet Zugang zu verschiedenen Di‐, Tri‐ und Tetra‐Ubiquitinketten. Photoinitiierte Thiol‐En‐Klickreaktionen werden dabei in Kombination mit einer Maskierungs‐ und Schutzgruppenstrategie zum kontrollierten Aufbau von Ubiquitinketten sowie zur Semisynthese von ...
Moritz Urschbach, Susanne Huhmann, Dominik Appel, Luca Ferrari, Dominik Vogl, Sascha Martens, Christian F. W. Becker   +6 more
wiley   +1 more source

Computational Insights into the Catalytic Mechanism of Is‐PETase: An Enzyme Capable of Degrading Poly(ethylene) Terephthalate

Chemistry – A European Journal, Volume 28, Issue 70, December 15, 2022., 2022
The enzyme is‐PETase degrades poly(ethylene) terephthalate (PET) at mesophilic temperatures. This makes is‐PETase a promising candidate for the biodegradation of this common pollutant. The energy profile for the degradation of a PET substrate mimic by is‐PETase was calculated by using computational quantum‐mechanical/molecular mechanical methods, and ...
Eugene Shrimpton‐Phoenix, John B. O. Mitchell, Michael Bühl   +2 more
wiley   +1 more source

TECHNOLOGY OF MISCANTHUS BIOMASS SACCHARIFICATION WITH COMMERCIALLY AVAILABLE ENZYMES

Вавиловский журнал генетики и селекции, 2015
We analyzed the possibility of using commercially available enzymes with cellulosolytic activity for saccharification of miscanthus biomass, Soranovsky variety, a new crop registered in Russia in 2013, in comparison to the saccharification of biomasses ...
T. N. Goryachkovskaya, K. V. Starostin, I. A. Meshcheryakova, N. M. Slynko, S. E. Peltek   +4 more
doaj  

Development of Improved Spectrophotometric Assays for Biocatalytic Silyl Ether Hydrolysis

Biomolecules
Reported herein is the development of assays for the spectrophotometric quantification of biocatalytic silicon−oxygen bond hydrolysis. Central to these assays are a series of chromogenic substrates that release highly absorbing phenoxy anions upon ...
Yuqing Lu, Chisom S. Egedeuzu, Peter G. Taylor, Lu Shin Wong   +3 more
doaj   +1 more source

Effects of Acute Asphyxia and Deep Hypothermia on the State of Binding of Lysosomal Acid Hydrolases in Canine Cardiac Muscle [PDF]

, 1967
Edith G. Leighty, Clinton D. Stoner, Mehdi M. Ressallat, G. Thomas Passananti, Howard D. Sirak   +4 more
openalex   +1 more source