Results 231 to 240 of about 297,801 (378)

Design of Potent Mannose‐6‐Phosphate Derivatives as Ligands for CI‐M6P/IGF2R Using Fluorescence Polarization Assay

Chemistry – A European Journal, EarlyView.
We designed and synthesized novel mannose‐6‐phosphate (M6P) derivatives to enhance their binding affinity for the CI‐M6P/IGF2 receptor, which plays a key role in lysosomal targeting. Using a fluorescence polarization assay, we evaluated di‐, tri‐, and penta‐M6P peptides and modified M6P analogs.
Lucie Mrázková, Klaudia Hladoníková, Barbora Toncarová, Michal Fischer, Jakub Zýka, Jaroslav Kozák, Michal Kráľ, Milan Kožíšek, Jiří Jiráček, Jakub Kaminský, Kamil Parkan, Lenka Žáková   +11 more
wiley   +1 more source

Genomic characterization and probiotic assessment of Bifidobacterium breve JKL2022 with strain-specific CLA-converting properties. [PDF]

Sci Rep
Elnar AG, Eum B, Kim GB.
europepmc   +1 more source

Unusual properties of retinyl palmitate hydrolase activity in rat liver.

, 1979
Earl H. Harrison, J. E. Smith, DeWitt S. Goodman   +2 more
openalex   +1 more source

Sph3 Is a Glycoside Hydrolase Required for the Biosynthesis of Galactosaminogalactan in Aspergillus fumigatus*♦

Journal of Biological Chemistry, 2015
N. C. Bamford, Brendan D. Snarr, Fabrice N Gravelat, D. J. Little, Mark J. Lee, Caitlin A. Zacharias, J. Chabot, Alexander M. Geller, Stefanie D. Baptista, Perrin Baker, H. Robinson, P. Howell, D. Sheppard   +12 more
semanticscholar   +1 more source

Convergent Approach Toward ADP‐Ribosylated Peptides via a Chemoselective Phosphate Condensation

Chemistry – A European Journal, EarlyView.
This research presents a convergent approach for synthesizing well‐defined ADP‐ribosylated peptides. It involves a regio‐ and chemoselective condensation of phosphoadenosyl (ADPr) fragments with phosphoribosyl peptides, allowing for the creation of various ADP‐ribosylated peptides, including a di‐ADP‐ribosylated‐peptide as the first example of a ...
Sven Wijngaarden, Femke L. A. M. van der Heijden, Cindy J. Bogaart, Maria Siskou, Ioanna Tsoumani, Daisy J. Robinson, Gijsbert A. van der Marel, Jeroen D. C. Codée, Herman S. Overkleeft, Dmitri V. Filippov   +9 more
wiley   +1 more source

ABHD18 degrades cardiolipin by stepwise hydrolysis of fatty acids. [PDF]

J Biol Chem
Ren M, Chen S, Greenberg ML, Schlame M.
europepmc   +1 more source

Regulated proteolysis of a cross-link–specific peptidoglycan hydrolase contributes to bacterial morphogenesis

Proceedings of the National Academy of Sciences of the United States of America, 2015
S. Singh, S. Parveen, L. Saisree, M. Reddy   +3 more
semanticscholar   +1 more source

Novel Para‐Phenylenediamine‐Based Derivatives as Receptor Tyrosine Kinase‐like Orphan Receptor 1 (ROR1) Inhibitors: An In Vitro Preliminary Characterization

ChemMedChem, EarlyView.
ROR1 represents a promising target for the development of novel antiproliferative compounds, giving its high expression in different cancer cell lines. The present study describes the workflow leading to the design, synthesis, and characterization of a series of para‐phenylenediamine‐based compounds able to interact with the target kinase, inhibiting ...
Gerardina Smaldone, Maria Rosaria Miranda, Francesca Di Matteo, Valeria Napolitano, Michela Aliberti, Simona Musella, Veronica Di Sarno, Gianluigi Lauro, Giuseppe Bifulco, Giacomo Pepe, Giovanna Aquino, Mario Felice Tecce, Isabel Maria Gomez‐Monterrey, Pietro Campiglia, Carmine Ostacolo, Alessia Bertamino, Vincenzo Vestuto, Tania Ciaglia   +17 more
wiley   +1 more source

Structural and functional analysis of Pseudomonas aeruginosa PelA provides insight into the modification of the Pel exopolysaccharide. [PDF]

J Biol Chem
Van Loon JC, Le Mauff F, Vargas MA, Gilbert S, Pfoh R, Morrison ZA, Razvi E, Nitz M, Sheppard DC, Howell PL.   +9 more
europepmc   +1 more source

EFFECT OF PROTEASE INHIBITORS OF ACTINOMYCETES ON LYSOSOMAL PEPTIDE-HYDROLASES FROM SWINE LIVER

, 1971
Hiroh Ikezawa, TOMIO TAKEUCHI, HAMAO UMEZAWA, TAKAAKI AOYAGI   +3 more
openalex   +2 more sources