Results 171 to 180 of about 102,009 (244)

Discrepancy in Reported and Observed Monoacylglycerol Lipase Inhibition of Aryl Formyl Piperidine Containing Potent and Highly Selective Monoacylglycerol Lipase Inhibitor. [PDF]

ChemMedChem
Savinainen JR, Singh PK, Yli-Kauhaluoma J, Patel JZ.   +3 more
europepmc   +1 more source

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

Epilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar, Majd A. AbuAlrob, Musab Ali, Simona Lattanzi, Boulenouar Mesraoua   +4 more
wiley   +1 more source

Isolation of Marine-Derived Microorganisms for PET Biodegradation. [PDF]

Microorganisms
Deng S, Guo Q, An Y, Liu Y, Yin J, Shi S, Wu T, Gu C, Tian X, Li Q.   +9 more
europepmc   +1 more source

Vaginal host–microbe signatures linked to placental outcomes in mares

Equine Veterinary Journal, EarlyView.
Abstract Background Ascending placentitis is a leading cause of late‐term pregnancy loss in mares. Although pathogens are presumed to ascend from the caudal reproductive tract, the association between the vaginal microbiome and placentitis has not been systematically examined.
Machteld van Heule, Babiche Heil, Jamie K. Norris, Kristene Gedye, Xiaoxiao Lin, Ward De Spiegelaere, Peter Daels, Pouya Dini   +7 more
wiley   +1 more source

Homogeneous Time-Resolved Fluorescence-Based Assay to Screen ADP-Ribosyl Hydrolase Inhibitors. [PDF]

Bio Protoc
Yu A, Wu D.
europepmc   +1 more source

Cross‐protective effect of a multicomponent fusion protein vaccine during a natural episode of Streptococcus zooepidemicus respiratory disease in ponies

Equine Veterinary Journal, EarlyView.
Abstract Background Streptococcus equi subspecies zooepidemicus is a highly diverse opportunistic pathogen of horses, associated with respiratory disease and endometritis. Objectives To characterise S. zooepidemicus isolates recovered from young ponies during a natural episode of respiratory disease, and to determine if vaccination with Strangvac®, a ...
Romain Paillot, J. Richard Newton, Sonia Gonzalez Medina, Sara Frosth, Lars Frykberg, Margareta Flock, Bengt Guss, Jan‐Ingmar Flock, Andrew S. Waller   +8 more
wiley   +1 more source

Draft genome sequences for two mucin-degrading bacteria isolated in Alabama. [PDF]

Microbiol Resour Announc
Gorman B, Hobson K, Higgins MA.
europepmc   +1 more source

Transforming the Landscape of Drug Innovation in AI Era: AlphaFold 3 and Beyond

Exploration, EarlyView.
Traditional drug development is time‐consuming and costly, and new tools are urgently needed to improve efficiency. This perspective reviews the considerable potential of AlphaFold 3 as a next‐generation predictive tool for drug discovery, particularly in target identification and validation, hit identification and lead optimization, and personalized ...
Songlin He, Liangbin Zhou, Xiaoshuai Wang, Chenzhong Li, Cheng Jiang, Rocky S. Tuan, Zhong Alan Li   +6 more
wiley   +1 more source

Pan-Genomic Characterization of the Nudix Hydrolase Gene Family and Its Response to Different Pathogen Strains in Maize (<i>Zea mays</i>). [PDF]

Genes (Basel)
Tang S, Zheng Y, Chen X, Zhang S, Li M, Wang W, Khan M, Xiao X, Nie Z, Pi B, Zhang S.   +10 more
europepmc   +1 more source

Mango Seed Valorization: Sustainable Source of Nutrients, Bioactives, and Value‐Added Applications

Food Chemistry International, EarlyView.
Highlighting mango seed as a valuable yet overlooked by‐product, promoting its utilization and reducing agroindustrial waste. ABSTRACT Mango (Mangifera indica L.) is one of the most widely cultivated tropical fruits, generating large quantities of by‐products during processing, with mango seed representing 20%–25% of the whole fruit weight ...
Priyanka Yadav, Mazia Ahmed, Unaiza Iqbal, Pinki Saini   +3 more
wiley   +1 more source