Results 11 to 20 of about 151,216 (363)
Structures and mechanisms of glycosyl hydrolases [PDF]
Structure, 1995 The wealth of information provided by the recent structure determinations of many different glycosyl hydrolases shows that the substrate specificity and the mode of action of these enzymes are governed by exquisite details of their three-dimensional structures rather than by their global fold.
Davies, G., Henrissat, Bernard
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Marine Extremophiles: A Source of Hydrolases for Biotechnological Applications
Marine Drugs, 2015 The marine environment covers almost three quarters of the planet and is where evolution took its first steps. Extremophile microorganisms are found in several extreme marine environments, such as hydrothermal vents, hot springs, salty lakes and deep-sea
Gabriel Zamith Leal Dalmaso +2 more
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Nature Microbiology, 2023 Bile salt hydrolases encoded by the gut microbiome shape the bile acid pool, including microbial conjugated bile acids, which impact Clostridioides difficile infection in the murine gut.
M. H. Foley +19 more
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Mechanism-Based Design of Efficient PET Hydrolases
ACS Catalysis, 2022 Polyethylene terephthalate (PET) is the most widespread synthetic polyester, having been utilized in textile fibers and packaging materials for beverages and food, contributing considerably to the global solid waste stream and environmental plastic ...
Ren Wei +10 more
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Epoxide Hydrolases: Multipotential Biocatalysts
International Journal of Molecular Sciences, 2023 Epoxide hydrolases are attractive and industrially important biocatalysts. They can catalyze the enantioselective hydrolysis of epoxides to the corresponding diols as chiral building blocks for bioactive compounds and drugs.
M. Bučko +4 more
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The Role of Glycoside Hydrolases in Phytopathogenic Fungi and Oomycetes Virulence
International Journal of Molecular Sciences, 2021 Phytopathogenic fungi need to secrete different hydrolytic enzymes to break down complex polysaccharides in the plant cell wall in order to enter the host and develop the disease.
V. Rafiei, H. Vélëz, G. Tzelepis
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Hydrolases: The most Diverse Class of Enzymes
Hydrolases [Working Title], 2022 Being the largest and most diverse class of enzymes, hydrolases offer an opportunity to explore the conformational diversity which forms the basis of their differential biological functions. In recent times, there is an urge to re-evaluate and update our
E. Shukla +2 more
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Microorganisms, 2021 Coral-associated microbes are crucial for the biology of their hosts, contributing to nutrient cycling, adaptation, mitigation of toxic compounds, and biological control of pathogens.
Caren Leite Spindola Vilela +5 more
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Soluble Epoxide Hydrolase Dimerization Is Required for Hydrolase Activity [PDF]
Journal of Biological Chemistry, 2013 Soluble epoxide hydrolase (sEH) plays a key role in the metabolic conversion of the protective eicosanoid 14,15-epoxyeicosatrienoic acid to 14,15-dihydroxyeicosatrienoic acid. Accordingly, inhibition of sEH hydrolase activity has been shown to be beneficial in multiple models of cardiovascular diseases, thus identifying sEH as a valuable therapeutic ...
Rishi M. Subrahmanyan +4 more
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Microorganisms, 2022 Lipases (EC 3.1.1.3) are hydrolases that catalyze triglycerides hydrolysis in free fatty acids and glycerol. Among the microorganisms that produce lipolytic enzymes, the entophytic fungi stand out.
Iracirema S. Sena +9 more
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