Results 31 to 40 of about 135,084 (297)

Structure- and context-based analysis of the GxGYxYP family reveals a new putative class of glycoside hydrolase. [PDF]

, 2014
BackgroundGut microbiome metagenomics has revealed many protein families and domains found largely or exclusively in that environment. Proteins containing the GxGYxYP domain are over-represented in the gut microbiota, and are found in Polysaccharide ...
Chang, Yuanyuan, Eberhardt, Ruth Y, Gilbert, Harry J, Godzik, Adam, Rigden, Daniel J, Xu, Qingping   +5 more
core   +2 more sources

Molecular characterization and functional annotation of a hypothetical protein (SCO0618) of A3(2) [PDF]

Genomics & Informatics, 2020
Streptomyces coelicolor is a gram-positive soil bacterium which is well known for the production of several antibiotics used in various biotechnological applications. But numerous proteins from its genome are considered hypothetical proteins.
Nadim Ferdous, Mahjerin Nasrin Reza, Md. Tabassum Hossain Emon, Md. Shariful Islam, A. K. M. Mohiuddin, Mohammad Uzzal Hossain   +5 more
doaj   +1 more source

Model for eukaryotic tail-anchored protein binding based on the structure of Get3 [PDF]

, 2009
The Get3 ATPase directs the delivery of tail-anchored (TA) proteins to the endoplasmic reticulum (ER). TA-proteins are characterized by having a single transmembrane helix (TM) at their extreme C terminus and include many essential proteins, such as ...
Ahmadian, Borgese, Boskovic, C. J. M. Suloway, Ching, Freymann, Georgiadis, Halic, Hann, Hemmingsson, J. W. Chartron, Jonikas, Kao, Koonin, Kutay, Lukasik, Lutkenhaus, M. Zaslaver, Milburn, Montoya, Netz, Ogura, Scheffzek, Schindelin, Schlessman, Schuldiner, Schuldiner, Shen, Sprang, Stefanovic, Tseng, W. M. Clemons, Wang, Zhou, Z    iga   +34 more
core   +3 more sources

Enzymes in the Content of Combined Antimicrobials as Improvers of Their Action

Вестник войск РХБ защиты
Accumulating information about the growing number of microorganisms that are resistant to the antibiotics used, on the one hand, and the emergence of information about the presence of laboratories in which closed work is carried out with microbial ...
N. A. Stepanov, A. G. Aslanli, M. V. Domnin, E. N. Efremenko   +3 more
doaj   +1 more source

Bacteriophage-encoded virion-associated enzymes to overcome the carbohydrate barriers during the infection process [PDF]

, 2017
Bacteriophages are bacterial viruses that infect the host after successful receptor recognition and adsorption to the cell surface. The irreversible adherence followed by genome material ejection into host cell cytoplasm must be preceded by the passage ...
Briers, Yves, Drulis-Kawa, Zuzanna, Maciejewska, Barbara, Majkowska-Skrobek, Grazyna, Łątka, Agnieszka   +4 more
core   +1 more source

The structure of a resuscitation-promoting factor domain from Mycobacterium tuberculosis shows homology to lysozymes [PDF]

, 2005
Resuscitation-promoting factor (RPF) proteins reactivate stationary-phase cultures of (G+C)-rich Gram-positive bacteria including the causative agent of tuberculosis, Mycobacterium tuberculosis.
AT Brunger, BA Johnson, Brian Henderson, Christian Roumestand, Claire Bagnéris, D Sharma, EJ van Asselt, EJ van Asselt, G Cornilescu, GV Mukamolova, GV Mukamolova, GV Mukamolova, H Song, JB Raymond, JG Lees, JL Pons, JM Tufariello, John Ward, JP Linge, L Holm, M Cohen-Gonsaud, M Cohen-Gonsaud, M Hartmann, Martin Cohen-Gonsaud, Nicholas H Keep, Philippe Barthe, R Koradi, RA Laskowski   +27 more
core   +2 more sources

Ethanol Induced Disordering of Pancreatic Acinar Cell Endoplasmic Reticulum: An ER Stress/Defective Unfolded Protein Response Model. [PDF]

, 2018
Background & aimsHeavy alcohol drinking is associated with pancreatitis, whereas moderate intake lowers the risk. Mice fed ethanol long term show no pancreas damage unless adaptive/protective responses mediating proteostasis are disrupted. Pancreatic
Abrol, Ravinder, Capri, Joseph, Cohn, Whitaker, Faull, Kym F, Freeman, Michael R, Lugea, Aurelia, Pandol, Stephen J, Piplani, Honit, Sakkiah, Sugunadevi, Su, Hsin-Yuan, Waldron, Richard T, Whitelegge, Julian P, Yang, Wei, Zhou, Bo   +13 more
core   +3 more sources

Active Site Mapping of Xylan-Deconstructing Enzymes with Arabinoxylan Oligosaccharides Produced by Automated Glycan Assembly [PDF]

, 2017
Xylan-degrading enzymes are crucial for the deconstruction of hemicellulosic biomass, making the hydrolysis products available for various industrial applications such as the production of biofuel.
de Kruijff, Goswinus H. M., Pfrengle, Fabian, Ruprecht, Colin, Schuhmacher, Frank, Seeberger, Peter H., Senf, Deborah, Simonetti, Sebastián Osvaldo   +6 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source