Results 11 to 20 of about 70,400 (263)
Dyna, 2022 Copoazú is a fruit originated from Colombian Amazon belonging to Theobroma genus, which includes species such as cacao raw material for chocolate. Both species presented similar processing stages, with different process parameters due to the physical ...
Jenifer Criollo nuñez +3 more
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Hydrolases: The most Diverse Class of Enzymes
Hydrolases [Working Title], 2022 Being the largest and most diverse class of enzymes, hydrolases offer an opportunity to explore the conformational diversity which forms the basis of their differential biological functions. In recent times, there is an urge to re-evaluate and update our
E. Shukla +2 more
semanticscholar +1 more source
Microorganisms, 2022 Lipases (EC 3.1.1.3) are hydrolases that catalyze triglycerides hydrolysis in free fatty acids and glycerol. Among the microorganisms that produce lipolytic enzymes, the entophytic fungi stand out.
Iracirema S. Sena +9 more
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Recent Advances in Peptidoglycan Synthesis and Regulation in Bacteria
Biomolecules, 2023 Bacteria must synthesize their cell wall and membrane during their cell cycle, with peptidoglycan being the primary component of the cell wall in most bacteria.
Anne Galinier +4 more
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Soluble Epoxide Hydrolase Dimerization Is Required for Hydrolase Activity [PDF]
Journal of Biological Chemistry, 2013 Soluble epoxide hydrolase (sEH) plays a key role in the metabolic conversion of the protective eicosanoid 14,15-epoxyeicosatrienoic acid to 14,15-dihydroxyeicosatrienoic acid. Accordingly, inhibition of sEH hydrolase activity has been shown to be beneficial in multiple models of cardiovascular diseases, thus identifying sEH as a valuable therapeutic ...
Jonathan W, Nelson +4 more
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Catalysis by nucleoside hydrolases [PDF]
Current Opinion in Structural Biology, 2003 Nucleoside hydrolases cleave the N-glycosidic bond of ribonucleosides. Because of their vital role in the protozoan purine salvage pathway, nucleoside hydrolases from parasitic protozoa in particular have been studied extensively by X-ray crystallography, kinetic methods and site-directed mutagenesis.
Versees, Wim, Steyaert, Jan
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(ADP-ribosyl)hydrolases: structure, function, and biology
Genes & Development, 2020 In this review, Rack et al. provide an overview of the different families of (ADP- ribosyl)hydrolases and discuss their molecular functions, physiological roles, and influence on human health and disease.
J. Rack, L. Palazzo, I. Ahel
semanticscholar +1 more source
Computational design of serine hydrolases
ScienceThe design of enzymes with complex active sites that mediate multistep reactions remains an outstanding challenge. With serine hydrolases as a model system, we combined the generative capabilities of RFdiffusion with a new ensemble generation method to ...
Anna Lauko +20 more
semanticscholar +2 more sources
The modular structure of α/β‐hydrolases
The FEBS Journal, 2020 The α/β‐hydrolase fold family is highly diverse in sequence, structure and biochemical function. To investigate the sequence–structure–function relationships, the Lipase Engineering Database (https://led.biocatnet.de) was updated.
Tabea L Bauer +2 more
semanticscholar +1 more source
Candida biome of severe early childhood caries (S-ECC) and its cariogenic virulence traits
Journal of Oral Microbiology, 2020 The protected niche of deep-caries lesions is a distinctive ecosystem. We assessed the Candida biome and its cariogenic traits from dentin samples of 50 children with severe-early childhood caries (S-ECC).
Kausar Sadia Fakhruddin +7 more
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