Results 11 to 20 of about 135,084 (297)
Structural genomics analysis of uncharacterized protein families overrepresented in human gut bacteria identifies a novel glycoside hydrolase. [PDF]
BackgroundBacteroides spp. form a significant part of our gut microbiome and are well known for optimized metabolism of diverse polysaccharides. Initial analysis of the archetypal Bacteroides thetaiotaomicron genome identified 172 glycosyl hydrolases and
Axelrod, Herbert L +7 more
core +2 more sources
Breaking the Cycle, Cholesterol Cycling, and Synapse Damage in Response to Amyloid-ß [PDF]
Soluble amyloid-β (Aβ) oligomers, a key driver of pathogenesis in Alzheimer disease, bind to cellular prion proteins (PrPC) expressed on synaptosomes resulting in increased cholesterol concentrations, movement of cytoplasmic phospholipase A2 (cPLA2) to ...
Bate, C
core +3 more sources
GGH (gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) [PDF]
Review on GGH (gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase), with data on DNA, on the protein encoded, and where the gene is implicated.
Cheng, Q, Evans, WE
openaire +2 more sources
Candida biome of severe early childhood caries (S-ECC) and its cariogenic virulence traits
The protected niche of deep-caries lesions is a distinctive ecosystem. We assessed the Candida biome and its cariogenic traits from dentin samples of 50 children with severe-early childhood caries (S-ECC).
Kausar Sadia Fakhruddin +7 more
doaj +1 more source
As β-glucosidases represent the major bottleneck for the industrial degradation of plant biomass, great efforts are being devoted to discover both novel and robust versions of these enzymes, as well as to develop efficient and inexpensive ways to produce
Juan A. Méndez-Líter +4 more
doaj +1 more source
Soluble Epoxide Hydrolase Dimerization Is Required for Hydrolase Activity [PDF]
Soluble epoxide hydrolase (sEH) plays a key role in the metabolic conversion of the protective eicosanoid 14,15-epoxyeicosatrienoic acid to 14,15-dihydroxyeicosatrienoic acid. Accordingly, inhibition of sEH hydrolase activity has been shown to be beneficial in multiple models of cardiovascular diseases, thus identifying sEH as a valuable therapeutic ...
Jonathan W, Nelson +4 more
openaire +2 more sources
The use of culture-independent approaches, such as metagenomics, provides complementary access to environmental microbial diversity. Mangrove environments represent a highly complex system with plenty of opportunities for finding singular functions.
Fábio Lino Soares +12 more
doaj +1 more source
Draft Genome Sequence of the Lignocellulose Decomposer Thermobifida fusca Strain TM51. [PDF]
Here, we present the complete genome sequence of Thermobifida fusca strain TM51, which was isolated from the hot upper layer of a compost pile in Hungary. T.
Beki +14 more
core +1 more source
To analyze the mechanisms involved in anthracene (ANT) degradation in the marine alga Ulva lactuca, total RNA was obtained from the alga cultivated without ANT and with 5 μM of ANT for 24 h, and transcriptomic analyses were performed.
Alberto González +10 more
doaj +1 more source
Characterization of key triacylglycerol biosynthesis processes in rhodococci. [PDF]
Oleaginous microorganisms have considerable potential for biofuel and commodity chemical production. Under nitrogen-limitation, Rhodococcus jostii RHA1 grown on benzoate, an analog of lignin depolymerization products, accumulated triacylglycerols (TAGs ...
Amara, Sawsan +5 more
core +2 more sources

