Results 81 to 90 of about 775,144 (299)
A Solvent-Topology Perspective on Hydrophobic Aggregation - DATA
6 filesA Solvent-Topology Perspective on Hydrophobic Aggregation - DATAPeer ...
Domínguez-Arca, Vicente
core +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
The role of hydrophobic matching on transmembrane helix packing in cells [PDF]
Folding and packing of membrane proteins are highly influenced by the lipidic component of the membrane. Here, we explore how the hydrophobic mismatch (the difference between the hydrophobic span of a transmembrane protein region and the hydrophobic ...
Vattulainen, Ilpo +17 more
core +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Superhydrophobic nanostructured coatings are a promising technology in construction engineering. This study developed a hydrophobic film through a simple mixing method, utilizing kaolin and polytetrafluoroethylene as additive particles, 1H,1H,2H,2H ...
Chen Anqi +4 more
doaj +1 more source
Ume Ruqia Tulain,1 Arshad Mahmood,2 Sidra Aslam,1 Alia Erum,1 Nadia Shamshad Malik,3 Ayesha Rashid,4 Rizwana Kausar,5 Mohammed S Alqahtani6 1College of Pharmacy, University of Sargodha, Sargodha, Pakistan; 2College of Pharmacy, Al Ain University, Abu ...
Tulain UR +7 more
doaj
This paper examines the efficacy of ionic liquid (IL) pretreatment on seven different commercially harvested biomass types: corn stover, miscanthus, pine, sorghum, sugarcane bagasse, switchgrass, and wheat straw in an effort to improve the production of ...
C. Luke Williams +4 more
doaj +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Water-repellent soil and its relationship to granularity, surface roughness and hydrophobicity: a materials science view [PDF]
Considerable soil water repellency has been observed at a wide range of locations worldwide. The soil exhibiting water repellency is found within the upper part of the soil profile.
Newton, Michael +5 more
core +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source

