Results 111 to 120 of about 179,806 (311)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

The hydrophobicity of surfaces with micro-structures [PDF]

, 2006
Micro/nano structures on the surface of the super-hydrophobic lotus leaves have been observed with Scanning Electron Microscope (SEM) images, and the hydrophobicity enhanced by rough structures on hydrophobic surface has attracted lots of interests. This
李战华, 郑旭, Silber-Li, Z (reprint author), Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech, Beijing 100864, Peoples R China.   +2 more
core   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Development of Polymer Hydrophobic Surfaces Through Combined Laser Ablation and Hot Embossing Processes

Journal of Manufacturing and Materials Processing
The development of hydrophobicity on polymer surfaces in mass production is one of the most critical challenges in the plastic industry. This paper deals with a novel combined hot embossing process in which femtosecond laser ablation is utilized to ...
Esmaeil Ghadiri Zahrani, Amirmohmmad Fakharzadeh Jahromi, Bahman Azarhoushang   +2 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Design Principles of Nitrogen‐Doped Carbon Catalysts for Oxygen Reduction Reaction

ChemElectroChem
Nitrogen‐doped carbon catalysts are attracting significant attention as alternative electrocatalysts to platinum owing to their high activity and durability in fuel cells’ oxygen reduction reaction (ORR), resource availability, and low catalyst cost ...
Kenji Hayashida, Bang Lu, Satoru Takakusagi, Junji Nakamura, Kotaro Takeyasu   +4 more
doaj   +1 more source

Intelligent Smart Coatings for Enhanced Corrosion Protection in Carbon Steel

Materials Proceedings
This study explores a new approach for corrosion protection of carbon steel, focusing on the application of polymeric coatings. Anticorrosive pigments were synthesized by loading 2-Mercaptobenzothiazole into zirconium oxide particles, and then an epoxy ...
Marwa A. Al-Ani, Ala H. Al-Ardah, Amal Mahgoub, Noora Aboumattar, Hadir Ibrahim, Muddasir Nawaz, R. A. Shakoor, Ahmed Radwan, Noora Al-Qahtani   +8 more
doaj   +1 more source

Influence of nicotine on the adherence of Candida albicans ATCC 14053 and Candida parapsilosis ATCC 22019 and expression of selected binding-related genes

Biotechnology & Biotechnological Equipment, 2017
Smoking is considered one of the main factors for development of dental plaque. Yeasts have been described to contribute to the plaque community. The aim of this study was to investigate the influence of nicotine on the growth of planktonic cells and ...
Shan Gunasegar, Wan Harun Himratul-Aznita   +1 more
doaj   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source