Results 91 to 100 of about 197,609 (259)
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Lightweight, surface hydrophobic, flame retardant and thermal insulating aerogels are highly needed for energy conservation and fire safety application. Herein, we reported silane modified MXene and polybenzazole (F-MP) nanocomposite aerogels prepared by
Gong, Li-Xiu +9 more
core +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
The development of hydrophobicity on polymer surfaces in mass production is one of the most critical challenges in the plastic industry. This paper deals with a novel combined hot embossing process in which femtosecond laser ablation is utilized to ...
Esmaeil Ghadiri Zahrani +2 more
doaj +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
erakhmatulina/Post-fire-hydrophobicity: First Release
This release accompanies the initial manuscript submission to the Hydrological Processes ...
erakhmatulina
core +1 more source
Design Principles of Nitrogen‐Doped Carbon Catalysts for Oxygen Reduction Reaction
Nitrogen‐doped carbon catalysts are attracting significant attention as alternative electrocatalysts to platinum owing to their high activity and durability in fuel cells’ oxygen reduction reaction (ORR), resource availability, and low catalyst cost ...
Kenji Hayashida +4 more
doaj +1 more source
Intelligent Smart Coatings for Enhanced Corrosion Protection in Carbon Steel
This study explores a new approach for corrosion protection of carbon steel, focusing on the application of polymeric coatings. Anticorrosive pigments were synthesized by loading 2-Mercaptobenzothiazole into zirconium oxide particles, and then an epoxy ...
Marwa A. Al-Ani +8 more
doaj +1 more source
Smoking is considered one of the main factors for development of dental plaque. Yeasts have been described to contribute to the plaque community. The aim of this study was to investigate the influence of nicotine on the growth of planktonic cells and ...
Shan Gunasegar +1 more
doaj +1 more source

