Results 81 to 90 of about 179,806 (311)

Hydrophobicity of Trigger factor. [PDF]

open access: yes, 2013
(A) Standard hydrophobicity of TF per residue [48], plotted as a coloured-barcode. The hydrophobicity scale varies from red – very hydrophilic (viz. ) – to green – very hydrophobic (viz. ).
Kushagra Singhal (397289)   +4 more
core   +1 more source

The Influence of Adding Silica Fluoroalkylsilane on the Morphology, Mechanical, and Corrosion Resistance Properties of Sol-Gel Derived Coatings

open access: yesEngineering Proceedings, 2023
Sol-gel-derived coatings’ corrosion resistance and mechanical properties have been studied frequently in the literature individually. However, there is a limitation in the studies that consider both mutually, as is common in all sol-gel hybrid coatings ...
Magdi Mussa   +2 more
doaj   +1 more source

Hydrophobization of a TIP60 Protein Nanocage for the Encapsulation of Hydrophobic Compounds

open access: yesChemPlusChem, 2023
AbstractEncapsulation of hydrophobic molecules in protein‐based nanocages is a promising approach for dispersing these molecules in water. Here, we report a chemical modification approach to produce a protein nanocage with a hydrophobic interior surface based on our previously developed nanocage, TIP60. The large pores of TIP60 act as tunnels for small
Maika Yamashita   +2 more
openaire   +2 more sources

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Study of the Lipid Profile of ATCC and Clinical Strains of Staphylococcus aureus in Relation to Their Antibiotic Resistance

open access: yesMolecules, 2019
A number of reports have indicated a relationship between bacterial resistance to antibiotics and their lipid composition. In the present study, we characterized the lipid profiles of American Type Culture Collection (ATCC) and clinical strains of ...
Carlo Bisignano   +10 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Enzyme Entrapped in Polymer-Modified Nanopores: The Effects of Macromolecular Crowding and Surface Hydrophobicity [PDF]

open access: yes, 2013
Macromolecular crowding is an ubiquitous phenomenon in living cells that significantly affects the function of enzymes invivo. However, this effect has not been paid much attention in the research of the immobilization of enzymes onto mesoporous silica ...
Jin, Qianru   +7 more
core   +1 more source

Effect of Leaf Surface Waxes on Leaf Colonization by Pantoea agglomerans and Clavibacter michiganensis

open access: yesMolecular Plant-Microbe Interactions, 2002
To evaluate the influence of leaf cuticular waxes on bacterial colonization of leaves, bacterial colonization patterns were examined on four glossy maize (Zea mays L.) mutants that were altered in their cuticular wax biosynthesis.
Lise M. Marcell, Gwyn A. Beattie
doaj   +1 more source

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