Results 91 to 100 of about 30,744 (233)

Matrix Metalloproteinase Inhibition in Melanoma

Experimental Dermatology, Volume 35, Issue 1, January 2026.
ABSTRACT Matrix metalloproteinases (MMPs) are involved in the degradation of the extracellular matrix (ECM) and are found to participate in all stages of tumour progression including modifying signalling pathways, regulating cytokines and promoting tumour growth, particularly by inducing angiogenesis and facilitating cancer spread.
Ellie Zhang, Varsha Thakur, Barbara Bedogni   +2 more
wiley   +1 more source

Development of Chemical Sensor Based on Fatty Hydroxamic Acid for The Determination of Vanadium (V) and Iron (Iii) Ions [PDF]

, 2005
Chemical sensor based on the use of uv-visible spectrophotometer and optical fibre reflectance spectrometer (OFRS) for the determination of Fe(II1) and V(V) ions have been developed in this study.
Isha, Azizul
core  

Pharmacological Effects of Anthranilic Hydroxamic Acid and Certain Other Hydroxamic Acids

Experimental Biology and Medicine, 1960
SummaryThe hydroxamate of anthranilic acid injected intraperitoneally into rats in a dose of 1.0 mg/g causes anesthesia lasting 10 hours or more. Recovery is apparently complete. One half this dose causes tranquilization and suppression of the conditioned avoidance response. The compound protects mice against twice the lethal dose of strychnine.
F. Bernheim, J. K. Stoops
openaire   +1 more source

Maize rhm1 Resistance to Bipolaris maydis Is Associated with Few Differences in Pathogenesis-Related Proteins and Global mRNA Profiles

Molecular Plant-Microbe Interactions, 2001
The maize rhm1 mutant resists Bipolaris maydis, the causal agent of Southern corn leaf blight, by producing small necrotic lesions surrounded by chlorotic haloes.
Carl R. Simmons, Susan Grant, Daniel J. Altier, Patrick F. Dowd, Oswald Crasta, Otto Folkerts, Nasser Yalpani   +6 more
doaj   +1 more source

Sp1 acetylation is associated with loss of DNA binding at promoters associated with cell cycle arrest and cell death in a colon cell line [PDF]

, 2010
Butyrate, a known histone deacetylase inhibitor (HDACi) and product of fibre fermentation, is postulated to mediate the protective effect of dietary fibre against colon cancer.
Benson, R.S.P., Bingle, C.D., Chirakkal, H., Corfe, B.M., Griffiths, J., Waby, J.S., Yu, C.W.   +6 more
core   +4 more sources

Multitarget Drugs: an Epigenetic Epiphany [PDF]

, 2016
Epigenetics refers to changes in a biological phenotype that are not due to an underlying change in genotype. In eukaryotes, epigenetics involves a set of chemical modifications of the DNA and the histone proteins in nucleosomes.
Atkinson, Baell, Baud, Beckers, Bentley, Blagodatski, Borretto, Bowman, Brand, Burg, Cai, Chen, Chen, Chen, Chen, Ciceri, Dancy, Deans, Fahy, Filippakopoulos, Finley, Fischer, Fuhrmann, Galloway, Gjertsen, Griffith, Guerrant, Guerrant, Hantschel, He, Huang, Hui, Hurley, Jing, Kaniskan, Kingston, Ko, Kortüm, Kozikowski, Lamblin, Lan, Ling, Liu, Lu, Lu, Maes, Mahboobi, Mahboobi, Mai, McGinty, McPherson, Micelli, Moore, Mottamal, Pachaiyappan, Pastor, Patel, Pereira, Pińa, Qian, Rask-Andersen, Rose, Rothbart, Rotili, Saijo, Saijo, Samatar, Schapira, Suganuma, Tavera-Mendoza, Villalba, Wagner, Winter, Wright, Yu, Yuan, Zhang, Zhang, Zhang, Zhang, Zhang, Zhao, Zheng, Zuo, Álvarez   +84 more
core   +1 more source

Enhancement of 2-hydroxy-3-naphthyl hydroxamic acid adsorption on bastnaesite and monazite surfaces using H2O2 pre-oxidation for improved flotation process

International Journal of Mining Science and Technology
Rare earth elements have been widely applied in various sectors. Bastnaesite and monazite are crucial rare earth minerals, and flotation is a vital technique for recovering fine-grained rare earth minerals and separating them from associated gangue ...
Weiwei Wang, Zhengyao Li, Anhua Zou, Kai Gao, Weiyao Zhu, Shaochun Hou, Chunlei Guo, Yuanyuan Wang   +7 more
doaj   +1 more source

Identification of isoform-selective hydroxamic acid derivatives that potently reactivate HIV from latency

Journal of Virus Eradication, 2019
Objectives: Current antiretroviral therapy can suppress HIV replication, increase CD4 count and result in increased lifespan. However, it cannot eradicate the virus due to the presence of latent provirus in cellular reservoirs, such as resting CD4+ T ...
Elleard F.W. Heffern, Rashmi Ramani, Garland Marshall, George B. Kyei   +3 more
doaj   +1 more source

Preparation of a Poly (Hydroxamic Acid) Ion-Exchange Resin from Poly (Ethyl Acrylate-Divinyl Benzene) Beads and its Properties. [PDF]

, 1988
A method to synthesize a poly (hydroxamic acid) chelating ion-exchange resin from poly (ethyl acrylate-divinyl benzene) and its behaviour towards some metal ions are described.
Ahmad, Zaharuddin, Wan Yunus, Wan Md Zin
core  

Histone deacetylase inhibition sensitizes osteosarcoma to heavy ion radiotherapy [PDF]

, 2015
Background: Minimal improvements in treatment or survival of patients with osteosarcoma have been achieved during the last three decades. Especially in the case of incomplete tumor resection, prognosis remains poor.
Blattmann, Claudia, Debus, Jürgen, Dittmar, Anne, Ehemann, Volker, Huber, Peter E., Kulozik, Andreas E., Oertel, Susanne, Roth, Eva, Stenzinger, Albrecht, Thiemann, Markus, Weichert, Wilko   +10 more
core   +1 more source