Pyrone-based inhibitors of metalloproteinase types 2 and 3 may work as conformation-selective inhibitors. [PDF]
, 2011 Matrix metalloproteinases are zinc-containing enzymes capable of degrading all components of the extracellular matrix. Owing to their role in human disease, matrix metalloproteinase have been the subject of extensive study.
de Oliveira, César AF +2 more
core +1 more source
Design, Synthesis, and Evaluation of Hydroxamic Acid-Based Molecular Probes for In Vivo Imaging of Histone Deacetylase (HDAC) in Brain [PDF]
, 2014 Hydroxamic acid-based histone deacetylase inhibitors (HDACis) are a class of molecules with therapeutic potential currently reflected in the use of suberoylanilide hydroxamic acid (SAHA; Vorinostat) to treat cutaneous T-cell lymphomas (CTCL).
Barth, Vanessa N. +10 more
core
Novel class of Bi(iii) hydroxamato complexes: synthesis, urease inhibitory activity and activity against H. pylori. [PDF]
, 2016 Reaction of Bi(NO3)3 with benzohydroxamic acid (Bha) and salicylhydroxamic acid (Sha) gives the novel Bi(iii) complexes [Bi2(Bha-1H)2(μ-Bha-1H)2(η(2)-NO3)2] () and [Bi6(CH3OH)2(η(1)-NO3)2(η(2)-NO3)(OH2)2(Sha-1H)12](NO3)2 ().
Fitzgerald-Hughes, Deirdre +3 more
core +1 more source
Synthesis and Characterization of Poly(Hydroxamic Acid) and Poly(Amidoxime) Chelating Resins from Polymer Grafted Sago Starch [PDF]
, 1999 The graft copolymerization of methyl acrylate (MA) onto sago starch was performed by free radical initiating process in which ceric ammonium nitrate (CAN) was used as an initiator.
Rahman, Md. Lutfor
core
Epigenetic treatment of solid tumours. A review of clinical trials [PDF]
, 2015 Epigenetic treatment has been approved by regulatory agencies for haematological malignancies. The success observe in cutaneous lymphomas represents a proof of principle that similar results may be obtained in solid tumours. Several agents that interfere
CODACCI PISANELLI, Giovanni +2 more
core +2 more sources
Al-Mustansiriyah Journal of Pharmaceutical SciencesA new hybrid molecule of Benzothiazole cross-linked with hydroxamic acid through an amino acid or aminoalkanoic acid were synthesised. All the synthesized hybrid molecules (1-5) were subjected to molecular docking studies to evaluate their binding ...
Mayssam Hazem, Shakir M. Alwan
doaj +1 more source
Molecules, 2019 New histone deacetylases (HDAC) inhibitors with low toxicity to non-cancerous cells, are a prevalent issue at present because these enzymes are actively involved in fibrotic diseases.
Viviana Pardo-Jiménez +2 more
doaj +1 more source
Removal of Hazardous Oxyanion Pollutants by Lanthanum (Iii) Hydroxide and Lanthanum (III) - Loaded Ion Exchangers [PDF]
, 2004 La(III) loaded poly(hydroxamic acid) chelating resin (LaPHA), lanthanum hydroxideloaded poly(hydroxamic acid) chelating resin (LaOHPHA) and lanthanum hydroxide (La(OH)3) were prepared and evaluated as sorbents for removal of As(V), As(III) and Cr(VI ...
Ahmed, Yehya M.
core
Khaya Cellulose Supported Copper Nanoparticles for Chemo Selective Aza-Michael Reactions [PDF]
, 2016 We prepared a highly active Khaya cellulose supported poly(hydroxamic acid) copper nanoparticles by the surface modification of Khaya cellulose through graft copolymerization and subsequently amidoximation.
Lutfor, M. R. +2 more
core
Cross metathesis-mediated synthesis of hydroxamic acid derivatives
Beilstein Journal of Organic Chemistry, 2018 An alternative synthesis of α,ß-unsaturated hydroxamates via cross metathesis between a class-I olefin and N-benzyloxyacrylamide is reported. The reaction proceeds better in the presence of Grubbs’ second generation catalyst within short time and in good
Shital Kumar Chattopadhyay +2 more
doaj +1 more source