Results 111 to 120 of about 21,287 (222)

Elaboration of the Effective Multi-Target Therapeutic Platform for the Treatment of Alzheimer's Disease Based on Novel Monoterpene-Derived Hydroxamic Acids. [PDF]

Int J Mol Sci, 2023
Aleksandrova Y, Munkuev A, Mozhaitsev E, Suslov E, Tsypyshev D, Chaprov K, Begunov R, Volcho K, Salakhutdinov N, Neganova M.   +9 more
europepmc   +1 more source

Orally Bioavailable Dual MMP-1/MMP-14 Sparing, MMP-13 Selective Alpha-sulfone Hydroxamates [PDF]

, 2010
A series of phenyl piperidine α-sulfone hydroxamate derivatives has been prepared utilizing a combination of solution-phase and resin-bound library technologies to afford compounds that are potent and highly selective for MMP-13, are dual-sparing of MMP ...
Becker, Daniel, Boehm, Terri L., Carroll, Jeffery N., Hockerman, Susan L., Kolodziej, Stephen A.   +4 more
core  

Hydroxamic acid-based histone deacetylase (HDAC) inhibitors can mediate neuroprotection independent of HDAC inhibition [PDF]

, 2014
Histone deacetylase (HDAC) inhibition improves function and extends survival in rodent models of a host of neurological conditions, including stroke, and neurodegenerative diseases.
Sleiman, Sama F.
core   +1 more source

Molybdenum-catalyzed enantioselective sulfoxidation controlled by a nonclassical hydrogen bond between coordinated chiral imidazolium-based dicarboxylate and peroxido ligands [PDF]

, 2018
Chiral alkyl aryl sulfoxides were obtained by molybdenum-catalyzed oxidation of alkyl aryl sulfides with hydrogen peroxide as oxidant in mild conditions with high yields and moderate enantioselectivities.
Carrasco Carrasco, Carlos Jesús, Galindo del Pozo, Agustín, Montilla Ramos, Francisco Javier   +2 more
core  

Enzymatic Synthesis and Application of Palm Oil-Based Fatty Hydroxamic Acids [PDF]

, 2004
Fatty hydroxamic acids (FHA) have been successfully synthesized from palm oils by a one-step lipase catalyzed reaction. Conversion of palm oils into the FHA was carried out by treating the substrate with hydroxylamine at 300C and neutral pH for 30 h ...
Suhendra, Dedy
core  

Synthesis and biological evaluation of C-4 substituted phenoxazine-bearing hydroxamic acids with potent class II histone deacetylase inhibitory activities. [PDF]

J Enzyme Inhib Med Chem, 2023
Chu JC, Tseng HJ, Lee SB, Hsu KC, Hsin LW, Liang RH, Lin TE, Gao NC, Chen LC, Lu WH, Wang AH, Huang WJ.   +11 more
europepmc   +1 more source

Redox-Neutral Selenium-Catalysed Isomerisation of para-Hydroxamic Acids into para-Aminophenols. [PDF]

Angew Chem Int Ed Engl, 2021
Chuang HY, Schupp M, Meyrelles R, Maryasin B, Maulide N.   +4 more
europepmc   +1 more source

DNA Binding, DNA Photocleavage, Molecular Docking Studies and Photo-Induced Effect on Melanoma Cells of 2-Methyl-3-OR Quinazolinone Derivatives

Biomolecules
Thirty 2-methyl-quinazolinone fussed hydroxamic acids (3-OH) and their 3-OEt and 3-OBn derivatives were evaluated for their affinity towards calf-thymus (CT) DNA using UV-vis absorption, viscosity and fluorescence spectroscopy. DNA photocleavage activity
Chrysoula Mikra, Stella Malichetoudi, Dimitrios Arampatzis, Ioanna Laskari, Maria Koffa, Ewelina Wieczorek-Szweda, Katerina R. Katsani, George Psomas, Konstantina C. Fylaktakidou   +8 more
doaj   +1 more source

Alternating Current Electrolysis as Efficient Tool for the Direct Electrochemical Oxidation of Hydroxamic Acids for Acyl Nitroso Diels-Alder Reactions. [PDF]

Angew Chem Int Ed Engl, 2021
Fährmann J, Hilt G.
europepmc   +1 more source

Molecular design, synthesis and in vitro biological evaluation of thienopyrimidine-hydroxamic acids as chimeric kinase HDAC inhibitors: a challenging approach to combat cancer. [PDF]

J Enzyme Inhib Med Chem, 2021
Abdel-Atty MM, Farag NA, Serya RAT, Abouzid KAM, Mowafy S.   +4 more
europepmc   +1 more source