Results 91 to 100 of about 21,287 (222)

Design of Fluorescent Coumarin-Hydroxamic Acid Derivatives as Inhibitors of HDACs: Synthesis, Anti-Proliferative Evaluation and Docking Studies

Molecules, 2020
Coumarin-hydroxamic acid derivatives 7a–k were herein designed with a dual purpose: as antiproliferative agents and fluorescent probes. The compounds were synthesized in moderate yields (30–87%) through a simple methodology, biological evaluation was ...
Santiago García, Itzel Mercado-Sánchez, Luis Bahena, Yolanda Alcaraz, Marco A. García-Revilla, Juvencio Robles, Nancy Santos-Martínez, David Ordaz-Rosado, Rocío García-Becerra, Miguel A. Vazquez   +9 more
doaj   +1 more source

Chromatin remodeling agents for cancer therapy [PDF]

, 2008
Alterations in chromatin structure profoundly influence gene expression during normal cellular homeostasis and malignant transformation. Methylation of cytosines within CpG islands located in promoter and proximal coding regions facilitates recruitment ...
Cinti, Caterina, Estenoz, Mariela, Giordano, Roberto, La Sala, Dario, Magnano, Anna   +4 more
core   +1 more source

From Mechanisms to Materials: Oximate Reactivity and Emerging Strategies for Organophosphate Detoxification

ChemPhysChem, Volume 27, Issue 7, 14 April 2026.
The development of effective strategies for the detoxification of organophosphorus (OP) nerve agents has evolved from the early mechanistic studies of François Terrier and collaborators, who first elucidated the exceptional nucleophilicity of α‐effect species such as oximes and hydroxamates, to the modern design of supramolecular and material‐based ...
Pedro Rodríguez‐Dafonte
wiley   +1 more source

Advances in non-Hydroxamate based Histone Deacetylase Inhibitors as Anticancer Agents [PDF]

Archives of Pharmaceutical Sciences Ain Shams University
The carcinogenesis process includes several epigenetic modifications that mainly target the silencing of tumor suppressor genes (TS genes) including ribonucleic acid (RNA) editing, deoxyribonucleic acid (DNA) hypermethylation and histone modification,
Nadine W. Nabiha, Maiy Y. Jaballahb, Rabah A.T. Serya, Khaled A.M. Abouzid   +3 more
doaj   +1 more source

Production of hydroxamic acids by immobilized Pseudomonas aeruginosa cells Kinetic analysis in reverse micelles [PDF]

, 2013
Intact cells from Pseudomonas aeruginosa strain L10 containing amidase were used as biocatalysts both free and immobilized in a reverse micellar system.
Bernardo, Marisa, Karmali, Amin, Pacheco, Rita, Serralheiro, Maria Luísa M.   +3 more
core   +1 more source

Engineered Biopolymer Architectures for Selective Metal Ions Extraction

Advanced Sustainable Systems, Volume 10, Issue 4, April 2026.
This review establishes a mechanism‐oriented framework that connects biopolymer chemistry, structural engineering, ligand design, and hydrometallurgical process variables for selective metal‐ion extraction. It analyzes how functional groups, hierarchical architectures, and solution speciation govern adsorption capacity and selectivity in acidic ...
Amir Nobahar, Helena Passos, Nicolas Schaeffer, Filipe H. B. Sosa, João A. P. Coutinho   +4 more
wiley   +1 more source

Monohydroxamic acids and bridging dihydroxamic acids as chelators to ruthenium(III) and as nitric oxide donors: syntheses, speciation studies and nitric oxide releasing investigations. [PDF]

, 2008
The synthesis and spectroscopic characterisation of novel mononuclear Ru(III)(edta)(hydroxamato) complexes of general formula [Ru(H2edta)(monoha)] (where monoha = 3- or 4-NH2, 2-, 3- or 4-C1 and 3-Me-phenylhydroxamato), as well as the first example of a ...
Celine J. Marmion (2069335), Celine Marmion (7895267), Darren Griffith (7895342), Jedd Comiskey (8010011), Kevin B. Nolan (262043), Krystyna Krot (8010008)   +5 more
core   +1 more source

Formation of fatty acids in photochemical conversions of saturated hydrocarbons [PDF]

Abiogenic synthesis of fatty acids was studied in photochemical conversions of saturated hydrocarbons. It was shown that, in a hydrocarbon water CaCO3 suspension, the action of 254 nm UV rays caused the formation of fatty acids with a maximum number of ...
Ladyzhenskaya, A. I., Pavlovskaya, T. Y., Telegina, T. A.   +2 more
core   +1 more source

Új, funkcionalizált peptidszármazékok előállítása és oldategyensúlyi vizsgálata = Synthesis and solution equilibrium studies of new, functionalised derivatives of peptides [PDF]

, 2008
A pályázat keretében 15 új peptidhidroxámsavat állítottunk elő és szisztematikusan megvizsgáltuk azt, hogy a ligandumok építőelemeinek (terminális aminocsoport jelenléte, a hidroxámsavcsoport nitrogénjének szubsztituense, a peptidlánc hossza, az ...
Buglyó, Péter, Bóka, Beáta, Farkas, Etelka, Nagy, Eszter Márta   +3 more
core  

Field-effect transistors assembled from functionalized carbon nanotubes

, 2006
We have fabricated field effect transistors from carbon nanotubes using a novel selective placement scheme. We use carbon nanotubes that are covalently bound to molecules containing hydroxamic acid functionality.
Appenzeller J., Auvray S., Avouris, Avouris Ph., Bachtold A., Bahr J. L., Banerjee S., Bethune D. S., Bonard J. M., Chen J., Chen Z., Cheng C., Choi K. H., Collins P. G., Cui Y., Dai H., Derycke V., Duan X., Dyke C. A., Folkers J. P., Hannon J. B., Heald C. G. R., Huang Y., Iijima S., Javey A., Jin S., Johnston D. E., Kataura H., Klinke C., Kooi S. E., Lee S. W., Lee Y. S., Lin Y. M., Martel R., McEuen P. L., Mirkin C. A., Morales A. M., Niyogi S., Perebeinos V., Radosavljevic M., Spataru C. D., Wind S. J.   +41 more
core   +1 more source