Results 101 to 110 of about 2,723 (289)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Growth Mechanism and Structural Correlations of Hydroxyapatites on Surface Functionalized Carbon Fibers

open access: yes, 2014
In this study, hydroxyapatites were deposited on surface modified carbon fibers using a simulated body fluid; different amounts of COOH functional group were formed on the fiber surfaces by different degrees of KOH pretreatment. The effect of the surface
Wen, S.Y.   +4 more
core   +1 more source

Bamboo‐Like Whiskers‐Reinforced Bioceramics Accelerate Large Segmental Bone Regeneration via Dual Modulation of Type‐H Vessels and Osteoinduction

open access: yesAdvanced Science, EarlyView.
The graphical abstract image of bamboo‐like whisker‐reinforced Ca‐P bioceramics accelerating large segmental bone regeneration. ABSTRACT Regenerative repair of segmental bone defect remains a major clinical challenge. The conventional mental implants suffer from mechanical strength mismatch and long‐term foreign bodies presence.
Cong Feng   +10 more
wiley   +1 more source

Aptamer‐Directed Porous DNA Nanocomposite Hydrogel for Active Pulp Preservation: Immunomodulation, Stem Cell Recruitment and Reparative Dentinogenesis

open access: yesAdvanced Science, EarlyView.
This study presents an injectable DNA‐based porous hydrogel integrating catechol motifs and targeting aptamers for pulpitis management. Upon in situ crosslinking, the scaffold actively recruits endogenous dental pulp stem cells, restores redox homeostasis, and modulates immune responses.
Luhui Cai   +9 more
wiley   +1 more source

Electrophoretic deposition of hydroxyapatite

open access: yesJournal of Materials Science: Materials in Medicine, 1997
Hydroxyapatite powders were prepared by a chemical precipitation method and electrophoretically deposited on Ti6Al4V surgical alloy substrates. The powders were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), particle size distribution and zeta potential measurements.
I, Zhitomirsky, L, Gal-Or
openaire   +2 more sources

Removal Cu(II) and Ni(II) by natural and synthetic hydroxyapatites : a comparative study

open access: yes, 2014
The sorption of divalent copper and nickel ions from aqueous solutions on natural and synthetic hydroxyapatites was investigated in batch mode at 25 and 40°C and over metal concentration range of 20–800 mg/L.
Boudia, Saliha   +2 more
core  

CD44‐Targeting Hydroxyapatite Nanoparticles (HAP) Induce Mitochondrial Dysfunction‐Driven PANoptosis and Immunogenic Cell Death (ICD) via Ca Overload in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Colorectal cancer (CRC) remains therapeutically challenging due to high metastasis, recurrence, and immunotherapy resistance driven by tumor microenvironment‐mediated immune evasion. Immunogenic cell death (ICD) offers a promising strategy to reshape the immune microenvironment, yet existing ICD inducers suffer from poor targeting efficiency ...
Yao Xiao   +12 more
wiley   +1 more source

A Bone Marrow–Mimetic Hydrogel Enables Dual‐Phase Hemostasis and Vascularized Osteogenesis for Cranial Defects

open access: yesAdvanced Science, EarlyView.
A biomimetic, fiber‐reinforced hydrogel (FE‐PDA@Fib/Gel‐TG) that enables dual‐phase cranial defect repair. The system provides: instant hemostasis in the early stage, and sustained co‐delivery of pro‐angiogenic and osteogenic signals for synergistic vascularized bone regeneration.
Lingbin Che   +9 more
wiley   +1 more source

Hydroxyapatites and nano-hydroxyapatites as scaffolds in drug delivery towards efficient bone regeneration: A review

open access: yesCarbohydrate Polymer Technologies and Applications
Bone regeneration is a complex process that requires materials capable of supporting structural integrity, promoting cell proliferation, and enabling effective drug delivery.
Amir Hatami kaleshtari   +6 more
doaj   +1 more source

Topologically Structured PLLA Fibers With Stress Concentration Effects for Health Monitoring

open access: yesAdvanced Science, EarlyView.
In this study, a multi‐path strategy was developed to enhance the piezoelectric properties of PLLA fibers through the stress concentration effect. The optimized devices generate piezoelectric output up to 14 times that of pure PLLA fibers. This piezoelectric enhancement strategy offers a new approach for high‐performance piezoelectric devices, with ...
Longfei Li   +8 more
wiley   +1 more source

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