Human IDO2 exhibits unique binding affinities distinct to those of human IDO1
Although indoleamine 2,3‐dioxygenase 2 (IDO2) is highly homologous to IDO1, it displays markedly lower catalytic activity. We found that IDO2 binds L‐tryptophan (L‐Trp) in a flipped orientation stabilized by the IDO2‐specific residue His143. Replacement of His143 with the IDO1‐equivalent tyrosine restored an IDO1‐like binding mode and increased ...
Shunsuke Nogi +8 more
wiley +1 more source
Biomaterials for Guided Tissue Regeneration and Guided Bone Regeneration: A Review. [PDF]
Duarte ND +7 more
europepmc +1 more source
ABSTRACT Introduction To evaluate the efficacy of dental varnishes/gels in the prevention/management of dental caries in older adults. Methods Cochrane, PubMed, Web of Science and EMBASE were searched through March 2024 for randomized controlled trials (RCT) including patients aged ≥ 60 years (or average age ≥ 60 years) utilizing varnish or gel ...
Theresa Cleary +3 more
wiley +1 more source
A Systematic Review Evaluating Methods for Diagnosis, Treatment and Prevention of Dental Erosions
ABSTRACT Aim The aim of this systematic review was to investigate the quality of evidence for methods used to diagnose, restore and prevent dental erosions, by evaluating and summarising clinical controlled studies and in situ studies covering this field.
Maria Skalsky Jarkander +5 more
wiley +1 more source
The Complex World of Toothpaste Diversity, Meeting Patient Clinical Needs. An Umbrella Review
ABSTRACT Background Amidst numerous recent advancements in toothpaste formulations and active ingredients, some clinicians may believe all toothpastes are similar despite differences in their active ingredients and corresponding clinical application.
Jeanie Suvan, Crystal Marruganti
wiley +1 more source
Gadolinium-Doped Hydroxyapatite Nanoparticles Functionalized with Curcumin and Folic Acid: Structural Insights and Magnetic Behavior for Theranostic Applications. [PDF]
Marinho JPN +8 more
europepmc +1 more source
Erosion Potential of Commercial Fluoride‐Free Mouthwashes on Dental Hard Tissues
ABSTRACT Purpose Mouthwashes often present acidic pH, which raises concerns about their potential contribution to erosive tooth wear. This study evaluated the erosive potential of commercial fluoride‐free mouthwashes using a screening method.
Astrid C. Valdivia‐Tapia +5 more
wiley +1 more source
Effectiveness of Recombinant Human Bone Morphogenetic Protein-2 in Socket Preservation: A Randomized Controlled Clinical and Sequential Human Histological Trial (BMP-2 TRIAL). [PDF]
Reddy SSP +7 more
europepmc +1 more source
ABSTRACT Purpose The aim of this in vitro study was to investigate the influence of bristle end design of toothbrushes and the relative enamel abrasivity (REA) of used toothpaste on the resulting abrasive enamel wear. Materials and Methods A total of 160 bovine enamel samples were allocated into eight groups (n = 20) and surface topography was recorded
Michelle S. Stübi +5 more
wiley +1 more source

