Results 71 to 80 of about 3,146 (276)

Gαi1/3 Are Essential for BMP2‐Induced Osteogenesis by Bridging BMP Receptors to the Gab1 Signaling Complex

Advanced Science, EarlyView.
The Gαi1/3 protein is a crucial connecting protein closely related to the signal transduction process of bone formation‐related cytokines such as BMP2. Gαi1/3 mediates downstream signaling pathways such as Smads and MAPK by binding to adaptor proteins like Gab1, thereby promoting the osteogenic effect of BMSCs.
Huajian Shan, Chaowen Bai, Yifei Zhu, Chenyang Xu, Sonngtao Li, Qize Sun, Chang She, Jinyu Bai, Cong Cao, Yitian Yang, Xiaozhong Zhou   +10 more
wiley   +1 more source

Synthesis and Antibacterial Property of Silver Doped Hydroxyapatite by Precipitation and Hydrothermal Method

Cailiao gongcheng, 2017
Nanorod Ag doped hydroxyapatites (Ag-HA) were synthesized by precipitation and hydrothermal method. Crystal structure, morphology and antibacterial property of prepared samples with silver contents prepared by different synthesis methods were ...
DENG Cheng, QI Xiao-peng, LI Qian, YIN Cong-ling, YANG Hui   +4 more
doaj   +1 more source

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

Advanced Science, EarlyView.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao, Qiuyi Li, Lingyun Wang, Chongao Zhang, Yutian Cheng, Shuang Liu, Fulan Wei, Zheqin Dong   +7 more
wiley   +1 more source

Surface fractal dimensions and textural properties of mesoporous alkaline-earth hydroxyapatites [PDF]

, 2013
This work examines the surface fractal dimensions (Df) and textural properties of three different alkaline-earth hydroxyapatites. Calcium, strontium and barium hydroxyapatite compounds were successfully synthesized via chemical precipitation method and ...
Granados-Correa, F., Barrera-Díaz, C.E., Vilchis-Granados, J.   +2 more
core   +1 more source

Self‐Assembly of Organic–Inorganic Copolymers Toward Bio‐Inspired Cementitious Composites

Advanced Science, EarlyView.
Organic–inorganic copolymerization of calcium silicate hydrate and thioctic acid produces a self‐organized nanocomposite inspired by the disordered collagen–mineral architecture of trabecular bone. The resulting material combines a compressive strength above 300 MPa with intrinsic physical reprocessibility, retaining over 80% of its strength and energy
Zonglin Xie, Suning Li, Fuwen Zhong, Gongkun Xiang, Mustapha Jamaa Garba, Yi Tian, Jun Wu, Zhiwu Yu, Qiang Yuan   +8 more
wiley   +1 more source

Chemical characterization of some substituted hydroxyapatites

Chemistry Central Journal, 2011
Synthetic multi-substituted hydroxyapatite nano powders containing silicon and or carbonate prepared by a wet chemical method. The process parameters are set up to allow the simultaneous substitution of carbonate and silicon ions in the place of ...
Ibrahim Doreya, Mostafa Amany A, Korowash Sara   +2 more
doaj   +1 more source

Machine Learning‐Driven Design of Multicomponent Bone Inorganic Matrix Mimicking Scaffolds for Osteogenesis Enhanced by Neurogenesis

Advanced Science, EarlyView.
Schematic illustration of development of experimental datasets and algorithm models, screening and preparation of the scaffolds and their applications in vivo. ABSTRACT Bone defects require materials with osteogenic, neurogenic, and angiogenic activity, yet designing such materials within high‐dimensional compositional spaces remains challenging. Here,
Kunlu Lin, Ying Yang, Chuyao Zhou, Hanyue Mao, Zhiquan Zhang, Libangxi Liu, Xiaoying Yu, Haoming Liu, Long Liu, Xiaoyan Wang   +9 more
wiley   +1 more source

Attachment and Proliferation of Osteoblasts on Lithium-Hydroxyapatite Composites

Advances in Materials Science and Engineering, 2012
The biocompatibility and bioactivity properties of hydroxyapatites (HAs) modified through lithium addition were investigated. Hydroxyapatites obtained from bovine bone were mixed with lithium carbonate (Li), in the proportions of 0.25, 0.50, 1.00, and 2 ...
Ana Paula M. Shainberg, Patrícia Valério, Alessandra Zonari, Faik N. Oktar, Lutfiye S. Ozyegin, Manuel Pedro F. Graça, Maria F. Leite, Alfredo M. Goes   +7 more
doaj   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

Magnesium incorporation into hydroxyapatite [PDF]

, 2010
The incorporation of Mg in hydroxyapatite (HA) was investigated using multinuclear solid state NMR, X-ray absorption spectroscopy (XAS) and computational modeling.
Jonathan C. Knowles, Robert J. Newport, Christel Gervais, Gervais, Christel, Bonhomme, C., Newport, Robert J., Smith, Mark,, Leeuw, Nora H. de, Francesco Mauri, Smith, Mark E., Neyvis Almora-Barrios, Christian Bonhomme, Nora H. de Leeuw, Wojciech Chrzanowski, Almora-Barrios, N., Mauri, F., Zhehong Gan, Knowles, J.C., Bonhomme, Christian, Newport, Robert, Knowles, Jonathan, Smith, Mark, E., Mark E. Smith, Knowles, Jonathan C., Wong, Alan, Laurencin, D., Almora-Barrios, Neyvis, Gan, Zhehong, Alan Wong, Smith, M.E., Chrzanowski, W., de Leeuw, Nora, H., Gervais, C., Danielle Laurencin, Laurencin, Danielle, de Leeuw, Nora H., Mauri, Francesco, de Leeuw, N.H., Chrzanowski, Wojciech, Wong, A., de Leeuw, Nora,, Gan, Z.   +41 more
core   +1 more source