Results 201 to 210 of about 59,669 (311)

Loss of SETD2 in wild‐type VHL clear cell renal cell carcinoma sensitizes cells to STF‐62247 and leads to DNA damage, cell cycle arrest, and cell death characteristic of pyroptosis

Molecular Oncology, Volume 19, Issue 4, Page 1244-1264, April 2025.
Vulnerability to the small molecule STF‐62247 is observed in SETD2‐inactivated VHL‐positive clear cell renal cell carcinoma (ccRCC) cells. DNA damage and loss of CDC25A leads to cell cycle arrest in S phase. Cleavage of caspase‐3 (CASP3) and gasdermin E (GSDME) suggests cell death by pyroptosis.
Mathieu Johnson, Sandra Turcotte
wiley   +1 more source

Hydroxychloroquine Use Is Associated with Lower Odds of Persistently Positive Antiphospholipid Antibodies and/or Lupus Anticoagulant in Systemic Lupus Erythematosus [PDF]

, 2012
Anna Broder, Chaim Putterman
openalex   +1 more source

Science, Politics and Hydroxychloroquine

Cardiology Research, 2020
openaire   +4 more sources

The Prognostic and Functional Impact of Multimorbidity in Systemic Sclerosis

ACR Open Rheumatology, Volume 7, Issue 4, April 2025.
Objective Our objective was to define the frequency and impact of multimorbidity in systemic sclerosis (SSc). Method Australian Scleroderma Cohort Study participants meeting American College of Rheumatology/EULAR criteria were included. Charlson Comorbidity Index scores were calculated at each visit, with multimorbidity defined as scores ≥4 ...
Jessica L. Fairley, Dylan Hansen, Susanna Proudman, Joanne Sahhar, Gene‐Siew Ngian, Diane Apostolopoulos, Jennifer Walker, Lauren V. Host, Wendy Stevens, Mandana Nikpour, Laura Ross   +10 more
wiley   +1 more source

Successful Management of Lupus-Associated Autoimmune Myelofibrosis with Tofacitinib: A Case Report. [PDF]

ACR Open Rheumatol
Soltani H, Dehghan A.
europepmc   +1 more source

Identification of Three Distinct Subgroups in Antiphospholipid Syndrome: Implication for Sex Differences and Prognostic Outcomes from a Multicenter Study

Advanced Science, Volume 12, Issue 15, April 17, 2025.
A large‐scale, multicenter, and two‐stage study is conducted to define antiphospholipid syndrome (APS) subgroups. By applying unsupervised K‐means clustering algorithm, the authors identified three distinct APS subgroups: obstetric APS, female thrombotic APS (tAPS), and male tAPS, which display marked differences in clinical manifestations and ...
Chen Chen, Ao Zhang, Jianhui Cheng, Zhongqiang Yao, Juan Meng, Yilu Qin, Qingyi Lu, Yufei Li, Xiangjun Liu, Tianhao Li, Chao Hou, Yundi Tang, Hongjiang Liu, Ning Xu, Sai Dong, Xinxin Li, Fangmin Xu, Jianping Guo, Chun Li   +18 more
wiley   +1 more source

Efficacy and safety of CFTR modulators in patients with interstitial lung disease caused by ABCA3 transporter deficiency. [PDF]

ERJ Open Res
Le Brun M, Nathan N, Louvrier C, Legendre M, Feuillet S, Frija-Masson J, Onanga M, Morer L, Debray MP, Fajac I, Burgel PR, Marchand-Adam S, Crestani B, Borie R.   +13 more
europepmc   +1 more source

Combined disease modifying treatment of rheumatoid arthritis with methotrexate and hydroxychloroquine

, 2009
N A Sergiets, Н. К. Еров
openalex   +1 more source

Hyperpigmentation Induced by Hydroxychloroquine

Dermatology Practical & Conceptual, 2023
openaire   +3 more sources

Hydroxychloroquine and pain thresholds [PDF]

Arthritis & Rheumatism, 1995
Gregg D. Middleton, Peter E. Lipsky, Jackie E. Mcfarlin   +2 more
openaire   +3 more sources