Results 101 to 110 of about 5,905,176 (286)

The simultaneous quantification of cytochrome P450 dependent linoleate and arachidonate metabolites in urine by HPLC-MS/MS

Journal of Lipid Research, 2002
A method for the simultaneous quantification of urinary linoleic and arachidonic acid derived epoxides and diols, as well as the arachidonate omega hydroxylated product has been developed. The method employs negative mode electrospray ionization and HPLC
John W. Newman, Takaho Watanabe, Bruce D. Hammock   +2 more
doaj   +1 more source

Decision letter for "Metabolomics reveals a correlation between hydroxyeicosatetraenoic acids (HETEs) and allergic asthma: evidence from three years' immunotherapy"

, 2021

openalex   +1 more source

Investigation of the selectivity of hydrogen abstraction in the nonenzymatic formation of hydroxyeicosatetraenoic acids and leukotrienes by autoxidation.

Journal of Biological Chemistry, 1985
The biosynthetic conversions of arachidonic acid to hydroperoxyeicosatetraenoic acids (HPETEs) and the further conversion of leukotriene epoxides are accompanied by stereoselective hydrogen abstraction from the reaction substrate.
A. Brash, A. Porter, R. L. Maas
semanticscholar   +1 more source

A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice. [PDF]

, 2014
It is well known that the ω-3 fatty acids (ω-3-FAs; also known as n-3 fatty acids) can exert potent anti-inflammatory effects. Commonly consumed as fish products, dietary supplements and pharmaceuticals, ω-3-FAs have a number of health benefits ascribed ...
Akiyama, Taro E, Armando, Aaron M, Bogner-Strauss, Juliane G, Chi, Tyler J, Chung, Heekyung, Cox, Jason M, Di Salvo, Jerry, Evans, Ronald M, Hah, Nasun, Lackey, Denise, Lagakos, William S, McNelis, Joanne, Oh, Da Young, Olefsky, Jerrold M, Pessentheiner, Ariane R, Powels, Mary Ann, Quehenberger, Oswald, Sasik, Roman, Sinz, Christopher, Walenta, Evelyn, Watkins, Steven M   +20 more
core   +1 more source

Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation [PDF]

, 2007
Dominik N. Müller, Cosima Schmidt, Eduardo Barbosa‐Sicard, Maren Wellner, Volkmar Groß, Hantz Hercule, Marija Marković, Horst Honeck, Friedrich C. Luft, Wolf‐Hagen Schunck   +9 more
openalex   +1 more source

Production of superoxide anion, prostaglandins, and hydroxyeicosatetraenoic acids by macrophages from hypersensitivity-type (Schistosoma mansoni egg) and foreign body-type granulomas [PDF]

, 1983
Stephen W. Chensue, Steven L. Kunkel, Gene I. Higashi, Peter A. Ward, Dov L. Boros   +4 more
openalex   +1 more source

Glucuronidation of oxidized fatty acids and prostaglandins B1 and E2 by human hepatic and recombinant UDP-glucuronosyltransferases

Journal of Lipid Research, 2004
Arachidonic acid (AA) can be metabolized to various metabolites, which can act as mediators of cellular processes. The objective of this work was to identify whether AA, prostaglandin (PG) B1 and E2, and 15- and 20-hydroxyeicosatetraenoic acids (15- and ...
Joanna M. Little, Mika Kurkela, Julia Sonka, Sirkku Jäntti, Raimo Ketola, Stacie Bratton, Moshe Finel, Anna Radominska-Pandya   +7 more
doaj   +1 more source

Localization of 12-hydroxyeicosatetraenoic acid in endothelial cells.

Journal of Lipid Research, 1990
Bovine aortic endothelial cells take up 12-hydroxyeicosatetraenoic acid (12-HETE), a lipoxygenase product formed from arachidonic acid. The uptake of [3H]12-HETE reached a maximum in 2 to 4 h. At this time, from 75 to 80% of the incorporated radioactivity was contained in phospholipids, about 85% of the esterified radioactivity remained in the form of ...
LX Wang, TL Kaduce, AA Spector
openaire   +3 more sources

High intake of n-6 polyunsaturated fatty acid exacerbates non-alcoholic steatohepatitis by the involvement of multiple metabolic pathways

Frontiers in Nutrition
Non-alcoholic steatohepatitis (NASH) is characterized by steatosis, inflammation, and hepatocyte damage. A Western-style diet characterized by excessive n-6 polyunsaturated fatty acid (n-6 PUFA) intake, which is metabolized to pro-inflammatory ...
Jian-Tong, Meng-Ting Zhou, Xiang-Zhun Song, Liu Yang, Yu-Hui Fang, Lan Liu, Jing-Shu Cui, Xiao-Chen Lu, Hai-Yang Zhu, Ying-Bin Jin, Hong-Mei Han   +10 more
doaj   +1 more source

12(S)‐Hydroxyeicosatetraenoic acid induces cAMP production via increasing intracellular calcium concentration [PDF]

, 2003
Go Hasegawa, Satoru Kumagai, Masato Yano, Yonggang Wang, Yuichi Kobayashi, Yuji Saito   +5 more
openalex   +1 more source