Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets [PDF]
Signal Transduction and Targeted Therapy, 2021 The arachidonic acid (AA) pathway plays a key role in cardiovascular biology, carcinogenesis, and many inflammatory diseases, such as asthma, arthritis, etc.
Bei Wang +8 more
doaj +3 more sources
Deuterated Arachidonic Acids Library for Regulation of Inflammation and Controlled Synthesis of Eicosanoids: An In Vitro Study [PDF]
Molecules, 2018 The synthesis of signal lipids, including eicosanoids, is not fully understood, although it is key to the modulation of various inflammatory states.
Dmitry V. Chistyakov +9 more
doaj +2 more sources
Pharmacometabolomics reveals racial differences in response to atenolol treatment. [PDF]
, 2013 Antihypertensive drugs are among the most commonly prescribed drugs for chronic disease worldwide. The response to antihypertensive drugs varies substantially between individuals and important factors such as race that contribute to this heterogeneity ...
Beitelshees, Amber L +12 more
core +10 more sources
The Polyunsaturated Fatty Acids Arachidonic Acid and Docosahexaenoic Acid Induce Mouse Dendritic Cells Maturation but Reduce T-Cell Responses In Vitro. [PDF]
PLoS ONE, 2015 Long-chain polyunsaturated fatty acids (PUFAs) might regulate T-cell activation and lineage commitment. Here, we measured the effects of omega-3 (n-3), n-6 and n-9 fatty acids on the interaction between dendritic cells (DCs) and naïve T cells. Spleen DCs
Johan A Carlsson +3 more
doaj +1 more source
Statin-induced myopathic changes in primary human muscle cells and reversal by a prostaglandin F2 alpha analogue [PDF]
, 2020 Statin-related muscle side effects are a constant healthcare problem since patient compliance is dependent on side effects. Statins reduce plasma cholesterol levels and can prevent secondary cardiovascular diseases.
Dittmar, Gunnar +10 more
core +1 more source
Biomolecules, 2020 Adrenic acid (AA), the 2-carbon elongation product of arachidonic acid, is present at significant levels in membrane phospholipids of mouse peritoneal macrophages.
Patricia Monge +6 more
doaj +1 more source
Emerging roles of polyunsaturated fatty acid synthesis pathway in colorectal cancer
Animal Cells and Systems, 2023 The development of colorectal cancer typically involves the accumulated influences of genetic alterations, medical issues, lifestyle, and diet. Dietary fatty acids appear to affect the tumorigenesis and progression of colorectal cancer.
Young-Ah Moon
doaj +1 more source
Proximate composition and fatty acids profiling of Seahorse originated from Simeulue, Aceh-Indonesia [PDF]
E3S Web of Conferences, 2022 The aim of this study was to determine the proximate composition, quantitative of fatty acids analysis as well as the content in the seahorse sample, Hippocampus sp which originated from Sibigo waters, Simeulue, Aceh, Indonesia.
Abdullah Abbas Muhammadar +4 more
doaj +1 more source
Frontiers in Pediatrics, 2021 Steroid-sensitive nephrotic syndrome is an immunological disorder mediated by still poorly defined circulating factor(s) that target the podocyte and damage the filtration barrier.
Stefano Turolo +14 more
doaj +1 more source
Journal of Lipid Research, 1985 The metabolism of the linolenic acid family (n-3) of fatty acids, e.g., linolenic, eicosapentaenoic, and docosahexaenoic acids, in cultured smooth muscle cells from rabbit aorta was compared to the metabolism of linoleic and arachidonic acids.
N Morisaki +7 more
doaj +1 more source